DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8249 and Y61A9LA.1

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_504243.2	Gene:	Y61A9LA.1 / 178849	WormBaseID:	WBGene00022014	Length:	526	Species:	Caenorhabditis elegans

Alignment Length:	543	Identity:	120/543 - (22%)
Similarity:	224/543 - (41%)	Gaps:	98/543 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 SESNGKQARIVSGLDRLLKTPPPGEQTRAVRRQV--------IAVILANVGVFSTG---MTLAMP 66
            |.|||.:..|.|...:    .|..|...|.||:|        :::.|.....|..|   ..|..|
Worm     3 SHSNGPRGSIASDDSQ----APLIEADDAQRRRVMPSLSIHILSIALCLSSGFQQGYIASVLNQP 63

  Fly    67 TATLHQ------LKDTTEPVHLNDSQASWFASVNALSAPI----GGLLSGFLLDRIGRKKSLIVL 121
            .|.:.|      ::.|..|:  :||......|:..:..||    |..|:|::..:.|||.:.::.
Worm    64 YAQIEQFINSSWIERTGHPI--SDSTLHLLWSLLNVCFPIATIFGQFLAGWMCSQFGRKHTALIA 126

  Fly   122 NVLIILAWILLAT-----PSESDQNAFFWQLIVSRFMLGVGMGLASAPPGVYAAEISVPKTRGSL 181
            :.|.|...:|.|.     |:       |..|.|.|.:..:..|:.:....|:..|.:.|:.||.:
Worm   127 SFLYIPGALLCAAAKWCFPA-------FELLFVGRIIWSLANGVNTVNATVWIVECAPPQIRGRM 184

  Fly   182 ILGTSISVAGG--ITILYGIGYCIRDDFRLIALICCGYQLVALLCVLPLPESHCWLLSK-KRVTE 243
            .......:|.|  :|...|:.:...:.:....|..|...:|:::....:.||..:::.| ..|..
Worm   185 AAMQEFFMALGSLLTQAVGVPFSTDELWPYNFLPNCAVVVVSMVMFSWVAESPQFIMEKYNDVDR 249

  Fly   244 AKRSLNYFRGFNKSDEITHPQVLEEFQLLQKSL----QQRNTA---------VKESF--WRNLHE 293
            |:::|..:.|.::.|    |.|..|.::.::|:    :::.||         ::..|  ||...:
Worm   250 ARKALAQYHGVSEDD----PSVESEIRICEQSIGKNKEKKKTAGGIESEHSGMEIMFMPWRAKDQ 310

  Fly   294 PE---VYKPLVILMSLFAF-----QQLTGIFVVIVFAVQ---ISQEAGIEIDPFMCAVLIGLARL 347
            ..   .|...|.:|...|:     :.|.|....|::.:.   .||...:       :...||.||
Worm   311 TSRLIRYCAWVGVMVKIAYVFTGARSLRGYSTFILYTLSHFTYSQATWL-------SFATGLLRL 368

  Fly   348 ITTCPMGYILEWWGRRRAGIISTL--GMSVCMFLLAGHSQIEILKEVPYLPVVAIVGFIVLSTLG 410
            ..|....::::..|||...|:|.|  .:|:.:.::|    |.|..|:.|...:.:...::::|.|
Worm   369 PFTLVPVFLVDRLGRRPLIIVSMLVSFVSILVMIIA----ININGELKYATFIGLTVLLLVNTCG 429

  Fly   411 LYTLPFFMISELFPQK-VRGPASGLTV-----AVGMFISFVVLKTYPGIKEYLGMSNCFIIFGVM 469
            :.::..|..:||.|:. :....|.||:     .:|:..:|     || ....:|..:..:.....
Worm   430 IGSVSRFYAAELVPRNLLLSSVSTLTMFEALTKIGVEFAF-----YP-TANVIGAQSLLLFLIPT 488

  Fly   470 ALFALIFVYLALPETRRRTLLEI 492
            .:|. :..||..|||.|.|:.|:
Worm   489 GVFT-VMCYLMCPETSRMTVNEV 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	100/484 (21%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	106/488 (22%)
Y61A9LA.1	NP_504243.2	MFS	42..504	CDD:391944	105/492 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920