Protein Alignment CG8249 and hmit-1.3

DIOPT Version :9

• Sequence 1: NP_001246349.1
• Gene: CG8249 / 36742
• FlyBaseID: FBgn0034045
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_497725.2
• Gene: hmit-1.3 / 175458
• WormBaseID: WBGene00010811
• Length: 604
• Species: Caenorhabditis elegans
• Alignment Length: 590
• Identity: 131/590 - (22%)
• Similarity: 219/590 - (37%)
• Gaps: 179/590 - (30%)

  Fly    83 NDSQASWFASVNALSAPIGGLLSGF--------LL------------------------------ 109
            :|.:..||..:.|.||.|||.|.|:        :|
 Worm    20 SDPKTGWFVYMLAFSAVIGGFLFGYDTGIVSAAMLYVPNASGIKPLDSVWQEIIVSITPGVAAIG 84

  Fly   110 --------DRIGRKKSLIVLNVLIILAWILLATPSESDQNAFFWQ---LIVSRFMLGVGMGLASA 163
                    |.:||||.:|..:|...:..|:.|..         |.   |::.|.:||:.:|.||.
 Worm    85 SLCSGPGSDFLGRKKIIIGASVTFTIGAIICAAA---------WTKIILLIGRILLGLAIGFASM 140

  Fly   164 PPGVYAAEISVPKTRGSLILGTSISVAGGITILYGIG----YCIRDD--FRLIALICCGYQLVAL 222
            ...:|.:|.|....||.|:.|..:.:..|:.|...||    |...|.  :||:........::..
 Worm   141 IVPIYVSEASPSHIRGKLVTGFQLMITVGLVIANIIGGAFSYVDPDQVGWRLMFAFAAVPAIIQF 205

  Fly   223 LCVLPLPESHCWLLSKKRVTEAKRSLNYFRGFNKSDEITHPQVLE-----EFQLLQKSLQQRN-- 280
            :|.|.||||..||....|..||:..|.  |.:|...|....::.|     |.:|..|:....|
 Worm   206 VCFLFLPESPRWLYEHGRTVEAREVLT--RIYNGHTEWVDYEINEISFSYEEELRAKAEHAGNGP 268

  Fly   281 TAVKESFWRNLHEPEVYKPLVILMSLFAFQQLTGIFVVIVFAVQISQEAGIEIDPFMCAVLIGLA 345
            |.:     |.|..|.|.|.::|...|..||||:||..|:.:...|.:.||::.:.....:.:|.:
 Worm   269 TII-----RILKTPHVRKAMIIGSLLQMFQQLSGINTVMYYTGNIIRSAGVKDNHTTIWISVGTS 328

  Fly   346 R---LITTCPMGYILEWWGRRRAGIISTLGMSVCMFLLA-------------------------- 381
            .   |.|..|:. ::|..|||...::|.:|  |.:||:|
 Worm   329 AINFLGTFIPIA-LVERVGRRVLLLVSMIG--VILFLIAMGVSFLLINNDSLRTFDQQNYTLNYN 390

  Fly   382 ------------------------GHSQIEILKE---VPY------------------------- 394
                                    |..:.::.|:   :|:
 Worm   391 PSVKHAAKCLKYSNCDFCVTDENCGFCESKVAKKGYCLPFPSDDSSDYSATGICEFSNLTNNGTD 455

  Fly   395 --------------LPVVAIVGFIVLSTLGLYTLPFFMISELFPQKVRGPASGLTVAVGMFISFV 445
                          ||::.:|.:::..:.|...||:.:.:|.:|...|..|..::.|.....:.:
 Worm   456 FEWEDTYCHTKFTVLPIIIMVFYLLSFSAGYAPLPWVLNAEFYPLWARSTAVSVSTACNWIFNLI 520

  Fly   446 VLKTYPGIKEYLGMSNCFIIFGVMALFALIFVYLALPETRRRTLLEIEEQF--RSGRSKSQNQAD 508
            |..|:..:.:.......|.|:....:.||:||:..:|||:..::.|:|..|  :..|.|:|...|
 Worm   521 VSLTFLSLSQAATKYGTFFIYCGCTMVALVFVFFFVPETKGYSIDEVEMLFMTKEERRKAQKVLD 585

  Fly   509 VEMKE 513
             |.||
 Worm   586 -ESKE 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	118/552 (21%)
		Sugar_tr	60..496	CDD:278511	123/569 (22%)
hmit-1.3	NP_497725.2	MFS	34..558	CDD:421695	114/542 (21%)
		MFS	<190..>249	CDD:421695	17/60 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158116
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740