Protein Alignment CG8249 and SLC2A12

DIOPT Version :9

• Sequence 1: NP_001246349.1
• Gene: CG8249 / 36742
• FlyBaseID: FBgn0034045
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_660159.1
• Gene: SLC2A12 / 154091
• HGNCID: 18067
• Length: 617
• Species: Homo sapiens
• Alignment Length: 627
• Identity: 132/627 - (21%)
• Similarity: 254/627 - (40%)
• Gaps: 156/627 - (24%)

  Fly     8 LNQNGS--ESNGKQARIVSGLDRLLKTPPPGEQTRAVRRQVIAVILANVGVFSTGMTLAMPTATL 70
            |||.|:  |:.|..:|           .||..:...:...:.:|..|..|:. .|..|.:.:..|
Human    13 LNQKGTAVETEGSGSR-----------HPPWARGCGMFTFLSSVTAAVSGLL-VGYELGIISGAL 65

  Fly    71 HQLKDTTEPVHLNDSQASWFASVNALSAPIGGLLSGFLLDRIGRKKSLIVLNVLIILAWILLATP 135
            .|:|..   :.|:..:.....|...:.|.:..|..|.|:||.||:.::|:.:.|:.|..::|..
Human    66 LQIKTL---LALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLIL- 126

  Fly   136 SESDQNAFFWQLIVSRFMLGVGMGLASAPPGVYAAEISVPKTRGSLILGTSISVAGGITILYGIG 200
                 :..:..|||.|..:||.:.|:|....||.|||:....||.|:....:.:..||...|...
Human   127 -----SLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISN 186

  Fly   201 YCIRDDFRLIALICCGYQ----LVALLCVLP------LPESHCWLLSKKRVTEAKRSLNYFRGFN 255
            |...:.|.       |::    ||..|.||.      ||.|..:|:.|.:...|.:.|...|..:
Human   187 YAFANVFH-------GWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRLRALS 244

  Fly   256 KSDEITHPQVLEEFQLLQKSLQQRNTAVKESFWRNLHEPEVYKPLVIL-MSLFAFQQLTGIFVVI 319
                    ...||..:::.||:..   .:.|||......:..:..::: ::|..|.|:||...::
Human   245 --------DTTEELTVIKSSLKDE---YQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNIL 298

  Fly   320 VFAVQISQEAGIEID--PFMCAVLIGLARLITTCPMGYILEWWGRR---------RAGIISTLGM 373
            .:|..:.:..|.:.:  ..:.:..:|:.::|:|.|...:::..|.:         .|..:.|:|:
Human   299 FYASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGI 363

  Fly   374 ----------SVC---------------------------------------------------- 376
                      .:|
Human   364 VNLNIHMNFTHICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLMPLRNDVDK 428

  Fly   377 -------MFLLAG--HSQIEILK---EVP----YLPVVAIVGFIVLSTLGLYTLPFFMISELFPQ 425
                   ..|.||  |::.:|:.   :||    :|.:.:::.::...::||..:|:.::||:||.
Human   429 RGETTSASLLNAGLSHTEYQIVTDPGDVPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPG 493

  Fly   426 KVRGPASGLTVAVGMFISFVVLKTYPGIKEYLGMSNCFIIFGVMALFALIFVYLALPETRRRTLL 490
            .:||.|..||.::...|:.::..|:..:.:.:|:.....|:.:|:|.:|:||.:.:|||:..:|
Human   494 GIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSL- 557

  Fly   491 EIEEQFRSGRSK-----------SQNQADVEMKEVFVRKPEE 521
               ||.....:|           |.:|.::..|:...|||:|
Human   558 ---EQISMELAKVNYVKNNICFMSHHQEELVPKQPQKRKPQE 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	109/529 (21%)
		Sugar_tr	60..496	CDD:278511	111/535 (21%)
SLC2A12	NP_660159.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29		7/26 (27%)
		Sugar_tr	44..561	CDD:306568	115/548 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144304
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750