Protein Alignment CG8249 and SLC2A14

DIOPT Version :9

• Sequence 1: NP_001246349.1
• Gene: CG8249 / 36742
• FlyBaseID: FBgn0034045
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001273166.1
• Gene: SLC2A14 / 144195
• HGNCID: 18301
• Length: 535
• Species: Homo sapiens
• Alignment Length: 514
• Identity: 127/514 - (24%)
• Similarity: 227/514 - (44%)
• Gaps: 86/514 - (16%)

  Fly    46 VIAVILANVGVFSTGMTLAM---PTATLHQL--KDTTEPVHLNDSQA----SWFASVNALSAPIG 101
            :.|:.:|.:|.|..|....:   |...:.:.  |..|:..:...|:.    .|..||...|  :|
Human    50 IFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAIFS--VG 112

  Fly   102 GLLS----GFLLDRIGRKKSLIVLNVLIILAWIL--LATPSESDQNAFFWQLIVSRFMLGVGMGL 160
            |::.    |..::|.||:.|::::|:|......|  |...:||.:     .||:.|.::|:..||
Human   113 GMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVE-----MLILGRLVIGLFCGL 172

  Fly   161 ASAPPGVYAAEISVPKTRGS--------LILGTSISVAGGITILYG--------IGYCIRDDFRL 209
            .:....:|..|||....||:        :::|..::...|:.::.|        :|:.|     |
Human   173 CTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTI-----L 232

  Fly   210 IALICCGYQLVALLCVLPLPESHCWLL-SKKRVTEAKRSLNYFRGFNKSDEITHPQVLEEFQLLQ 273
            .|::    |..||.|   .|||..:|| ::|:...|.|.|....|..        .|.::.|.::
Human   233 PAIL----QSAALPC---CPESPRFLLINRKKEENATRILQRLWGTQ--------DVSQDIQEMK 282

  Fly   274 ----KSLQQRNTAVKESFWRNLHEPEVYKPLVILMSLFAFQQLTGIFVVIVFAVQISQEAGIEID 334
                :..|::...|.|.|..:.:.    :|::|.:.|...|||:||..|..::..|.::||:: .
Human   283 DESARMSQEKQVTVLELFRVSSYR----QPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQ-Q 342

  Fly   335 PFMCAVLIGLARLITTCPMGYILEWWGRRRAGIISTLGMSVCMFLLAGHSQIEILKE-----VPY 394
            |....:..|:...|.|....:::|..|||...:|...||:.|..|:.    :.:|.:     :.:
Human   343 PIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMT----VSLLLKNHYNGMSF 403

  Fly   395 LPVVAIVGFIVLSTLGLYTLPFFMISELFPQKVRGPASGLTVAVGMFISFVVLKTYPGIKEYLGM 459
            :.:.||:.|:....:|...:|:|:::|||.|..|..|..:........:|:|...:|....|||
Human   404 VCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLG- 467

  Fly   460 SNCFIIFGVMALFALIFVYLALPETRRRTLLEIEEQF--------RSGRSKSQNQADVE 510
            :..||||....:..|.|.:..:||||.||..:|...|        |||:........:|
Human   468 AYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHGADRSGKDGVMGMNSIE 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	114/470 (24%)
		Sugar_tr	60..496	CDD:278511	118/476 (25%)
SLC2A14	NP_001273166.1	MFS	53..487	CDD:119392	114/470 (24%)
		Sugar_tr	54..504	CDD:278511	121/486 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143984
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840