Protein Alignment CG8249 and SLC2A13

DIOPT Version :9

• Sequence 1: NP_001246349.1
• Gene: CG8249 / 36742
• FlyBaseID: FBgn0034045
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_443117.3
• Gene: SLC2A13 / 114134
• HGNCID: 15956
• Length: 648
• Species: Homo sapiens
• Alignment Length: 654
• Identity: 142/654 - (21%)
• Similarity: 245/654 - (37%)
• Gaps: 177/654 - (27%)

  Fly     8 LNQNGSESNGKQARIVSGL--DRLLKTPPP-------------------------------GEQT 39
            :::..||:.....|.:|.|  :|..|.|.|                               |:..
Human     1 MSRKASENVEYTLRSLSSLMGERRRKQPEPDAASAAGECSLLAAAESSTSLQSAGAGGGGVGDLE 65

  Fly    40 RAVRRQ-----------VIAVILA--------NVGVFSTGMTLAMPTATLHQLKDTTEPVHLNDS 85
            ||.|||           |:||..|        :.||.|..|.|.....:|..|..     .|..|
Human    66 RAARRQFQQDETPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDALWQ-----ELLVS 125

  Fly    86 QASWFASVNALSAPIGGLLSGFLLDRIGRKKSLIVLNVLIILAWILLATPSESDQNAFFWQLIVS 150
            .....|:|:||:   ||.|:|.    .||:.::::.:.|......:||..:..:      .|:..
Human   126 STVGAAAVSALA---GGALNGV----FGRRAAILLASALFTAGSAVLAAANNKE------TLLAG 177

  Fly   151 RFMLGVGMGLASAPPGVYAAEISVPKTRGSLILGTSISVAGG---ITILYG-IGYCIRDDFRLIA 211
            |.::|:|:|:||....||.||:|.|..||.|:...::.:.||   .:::.| ..|..:|.:|.:.
Human   178 RLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYML 242

  Fly   212 LICCGYQLVALLCVLPLPESHCWLLSKKRVTEAKRSLNYFRGFNKSDEITHPQVLEEFQLLQKSL 276
            .:.....::.....|.||||..||:.|.:..:|:|.|:..||....|        ||:..::.::
Human   243 GLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMRGNQTID--------EEYDSIKNNI 299

  Fly   277 QQRNTAVKES---FWRNLHEPEVYKPLVILMSLFAFQQLTGIFVVIVFAVQISQEAGIEID--PF 336
            ::....|..:   ..|.|..|...:.|::...|..||||:||..::.::..|.|.:|:|.|  ..
Human   300 EEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAI 364

  Fly   337 MCAVLIGLARLITTCPMGYILEWWGRRRAGIISTLGMSVCMFLLA-GH-SQIEILKEVPYLPV-- 397
            ..|.:......|.|....:::|..|||:....|..|.:|.:.:|| |. ...::...:.:.|:
Human   365 WLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQVSPRITFKPIAP 429

  Fly   398 ----------------------------------------------------------------- 397
                                                                             
Human   430 SGQNATCTRYSYCNECMLDPDCGFCYKMNKSTVIDSSCVPVNKASTNEAAWGRCENETKFKTEDI 494

  Fly   398 -------------VAIVG---FIVLSTLGLYTLPFFMISELFPQKVRGPASGLTVAVGMFISFVV 446
                         .|::|   ::|....|:..:|:.:.||::|...|...:..:..:....:.:|
Human   495 FWAYNFCPTPYSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLV 559

  Fly   447 LKTYPGIKEYLGMSNCFIIFGVMALFALIFVYLALPETRRRTLLEIEEQFRS-----GRSKSQNQ 506
            ..|:....|||.....|.::...|...|:|:|..||||:.:.|.|||..|.:     |.|.|...
Human   560 SLTFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFDNRLCTCGTSDSDEG 624

  Fly   507 ADVE 510
            ..:|
Human   625 RYIE 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	111/531 (21%)
		Sugar_tr	60..496	CDD:278511	115/529 (22%)
SLC2A13	NP_443117.3	Sugar_tr	84..609	CDD:278511	121/550 (22%)
		MFS	86..591	CDD:119392	111/530 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144088
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D524131at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750