DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8249 and slc2a3

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	XP_031762189.1	Gene:	slc2a3 / 100497763	XenbaseID:	XB-GENE-921721	Length:	499	Species:	Xenopus tropicalis

Alignment Length:	498	Identity:	128/498 - (25%)
Similarity:	228/498 - (45%)	Gaps:	55/498 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 VIAVILANVGVFSTGMTLAMPTATLHQLKD----TTEPVHLNDSQASWFASVNALSAPI------ 100
            |.||.:|.:|....|....:..|....:|.    |.|..:..:...|...|:.:||..|
Frog    20 VFAVCVAAIGSLQFGYNTGVINAPEKIIKSFYNGTYEHRYGKEISESLLTSLWSLSVAIFSVGGM 84

  Fly   101 -GGLLSGFLLDRIGRKKSLIVLNVLIILAWILLATPSESDQNAFFW---QLIVSRFMLGVGMGLA 161
             |.|..||..:|.||:.:::::||..|:..:.:..      :...|   .||:.||::|:..||.
Frog    85 VGSLSVGFFANRFGRRNAMLLVNVAAIVGGVFMGF------SKLAWSPEMLIIGRFIIGIFCGLC 143

  Fly   162 SAPPGVYAAEISVPKTRGSLILGTSISVAGGITI--LYGIGYCIRDDFRLIALICCGYQLVALLC 224
            :....:|..|::....||:|.....:.:..||.:  ::|:.:.:..:.....|:.....|..:.|
Frog   144 TGLVPMYIGELAPTSLRGALGTLNQLGIVVGILVAQIFGLEFILGSETLWPLLLGLTVFLSIIQC 208

  Fly   225 V-LPL-PESHCWLL-SKKRVTEAKRSLNYFRGFNKSDEITHPQVLEEFQLLQKSLQQRNTAVKES 286
            | ||. |||..:|| .||...:|:|.|...||  .:|..:..|.:::..  .::..:::.::.|.
Frog   209 VLLPFCPESPRYLLIVKKEDEKAERILRKLRG--TTDVASDVQEMKDES--ARTAAEKSVSILEI 269

  Fly   287 FWRNLHEPEVYKPLVILMSLFAFQQLTGIFVVIVFAVQISQEAGIEIDPFMCAVLIGLARLITTC 351
            |    ...:..:|:.|.:.|...|||:||..|..::..|.::||:. :|....:..|:...:.|.
Frog   270 F----RSSQYRQPITIAIILQLSQQLSGINAVFYYSTSIFEDAGVP-NPVYATIGAGVVNTVFTV 329

  Fly   352 PMGYILEWWGRRRAGIISTLGMSVCMFLLAGHSQIEI-LKEV----PYLPVVAIVGFIVLSTLGL 411
            ....|:|..|||...:....||:|...::.    |.: |||.    .|:.:|||..|:.|..:|.
Frog   330 VSLLIVERAGRRTLQLTGLGGMAVGALIMT----IALKLKEQDQAWSYVSIVAIYCFVALFEIGP 390

  Fly   412 YTLPFFMISELFPQKVRGPASGLTVAVGMFISFVVLKTYP----GIKEYLGMSNCFIIFGVMALF 472
            ..:|:|:::|||.|..|..|..::.......:|:|...:|    |...|:     |:||.|:.:.
Frog   391 GPIPWFIVAELFSQGPRPAAMAISGCSNWTANFLVGMLFPYAAKGCGPYV-----FLIFMVLLIL 450

  Fly   473 ALIFVYLALPETRRRTLLEIEEQF---RSGRSKSQNQADVEMK 512
            ..|:.:..:||||.||..:|.::|   ...|:||.:.....||
Frog   451 FFIYTFFKVPETRGRTFEDIAQEFEMPERSRTKSDSVQMTGMK 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	113/457 (25%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	117/463 (25%)
slc2a3	XP_031762189.1	MFS_GLUT_Class1	21..465	CDD:340989	118/467 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000