DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8249 and slc2a11.2

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001339156.1	Gene:	slc2a11.2 / 100496725	XenbaseID:	XB-GENE-5857129	Length:	489	Species:	Xenopus tropicalis

Alignment Length:	499	Identity:	131/499 - (26%)
Similarity:	239/499 - (47%)	Gaps:	75/499 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 VIAVILANVGVFSTGMTLAM---PTATLHQ-LKDTTE-----PVHLNDSQASW--FASVNALSAP 99
            ::.::|...|.|..|:.:::   |...:.: :.||.:     |:|.:.....|  ..||.::...
Frog    16 LLCLVLGIGGTFQYGLHISLINSPAEYIQKFINDTWQHRYGSPLHPDKITLFWSFIVSVYSIGGL 80

  Fly   100 IGGLLSGFLLDRIGRKKSLIVLNVLIIL--AWILLATPSESDQNAFFWQLIVSRFMLGVGMGLAS 162
            :|.|:.|:|....||||:.:..||..:|  |.::|:..::|     |..:||.||:.||..|::.
Frog    81 MGSLIVGYLSVSFGRKKTQLYNNVFALLGAALMMLSPVAQS-----FEMIIVGRFLYGVNTGVSL 140

  Fly   163 APPGVYAAEISVPKTRGSLILGTSISVAGGITILYGIGYCIRDDFRLIAL------ICCGYQLVA 221
            ....:|..|.:..|.|| :.:..|:.:|.|..:.:.:|  :|:.....||      ......||.
Frog   141 NLHTMYIGECAPKKLRG-ISVTVSLFIALGKLMGFVVG--LREFLGSEALWPYLMSFSAVPALVQ 202

  Fly   222 LLCVLPLPESHCWLL----SKKRVTEAKRSLNYFRGFNKSDEITHPQVLEEFQLLQKSL--QQRN 280
            ||.:...|||..:||    :|:...:|.:.|     :...|   |...:::....:.||  :||.
Frog   203 LLTLPFFPESPRYLLIDKDNKEGCLKAMQQL-----WGAGD---HVAEMDDMLAEKNSLEGEQRK 259

  Fly   281 ---TAVKESFWRNLHEPEVYKPLVILMSLFAFQQLTGIFVVIVFAVQISQEAGI---EIDPFMCA 339
               ..:|:...|       ::.:.|:::..|. |||||.||..:|..:.:.|||   :| ||: :
Frog   260 GVMDLLKKRCVR-------WQMISIVLTCGAI-QLTGINVVYFYAYDVFRNAGIPDRQI-PFI-S 314

  Fly   340 VLIGLARLITTCPMGYILEWWGRR-----RAGIISTLGMSVCMFLLAGHSQIEILKEVPYLPVVA 399
            :.||:...:||...|::::..||:     ..|:| ||.:|:   |.|..|..::...:||.....
Frog   315 LGIGVTEALTTVLCGFVIDRMGRKPLLWINYGVI-TLTLSL---LTATLSLQDLHSWMPYFSSAL 375

  Fly   400 IVGFIVLSTLGLYTLPFFMISELFPQKVRGPASGLTVAV----GMFISFVVLKTYPGIKEYLGMS 460
            |..|.:...||...:...:.:|:|.|..| ||:.:.:.:    ||||   :..::|.::..|| :
Frog   376 IFIFTLSFGLGPGGVSCVIPTEMFVQSYR-PAAYMLIGILNWLGMFI---LAWSFPFMEAALG-A 435

  Fly   461 NCFIIFGVMALFALIFVYLALPETRRRTLLEIEEQFRSGRSKSQ 504
            .||:.|.::.:...||.:|.||||:.:::|||.:.|.....:.|
Frog   436 FCFVFFIILCICMGIFSFLILPETKNKSILEILDSFNQLNFRQQ 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	121/469 (26%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	126/475 (27%)
slc2a11.2	NP_001339156.1	MFS	22..467	CDD:391944	126/479 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910