DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8249 and slc2a9

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	XP_002936818.2	Gene:	slc2a9 / 100495427	XenbaseID:	XB-GENE-5883703	Length:	514	Species:	Xenopus tropicalis

Alignment Length:	457	Identity:	122/457 - (26%)
Similarity:	204/457 - (44%)	Gaps:	70/457 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 SVNALSAPIGGLLSGFLLDRIGRKKSLIVLNVLIILAWILL------ATPSESDQNAFFWQLIVS 150
            ||.||...:|.||.|.|:.|.|||.::|....|:.:|..|:      ::|.         .:|:.
Frog    80 SVFALGGMLGSLLVGILVSRFGRKGTIIRSTPLVFVAGGLMGLSRIFSSPE---------MVIIG 135

  Fly   151 RFMLGVGMGLASAPPGVYAAEISVPKTRGSLILGTSISVAGGI--TILYGIGYCIRDD-----FR 208
            ||:.|:..|::.:...:|..|||....||.|.|..||.:..|:  ..:.|:...:..|     |.
Frog   136 RFITGIHSGISLSVVPMYLGEISPKNLRGLLGLVPSIFICLGVFSAQVLGLPELLGQDETWPLFL 200

  Fly   209 LIALICCGYQLVALLCVLP-LPESHCWLL-SKKRVTEAKRSLNYFRGFNKSDEITHPQVLEEFQL 271
            .:.::....|||    :|| .|||..:|| .|..|.....:|..|.|     |.....|:||.|.
Frog   201 SLVVVPTFVQLV----LLPWFPESPRYLLIDKSNVHGTIDALRCFLG-----EYDVQDVIEEMQE 256

  Fly   272 LQKSLQQRNTAVKESFWRNLHEPEVYKPLVILMSLFAFQQLTGIFVVIVFAVQISQEAGI---EI 333
            .|||....:|.   |..:.|.:|.::..::.::.:....||:||..:..:...|.:.|||   ||
Frog   257 EQKSFSSVDTV---SVCQFLSDPTLFWQILSVIVINIGMQLSGIDAIWFYTNSIFENAGIPMAEI 318

  Fly   334 DPFMCA------VLIGLARLITTCPMGYILEWWGRRRAGIISTLGMSVCMFLLAG-------HSQ 385
             |:...      ::.||....|...:|        ||..:|.  |.|...|..||       .::
Frog   319 -PYTTVGTGAIEIVAGLIGCFTVEKLG--------RRPLLIG--GFSFMGFCCAGITLALVFQAR 372

  Fly   386 IEILKEVPYLPVVAIVGFIVLSTLGLYTLPFFMISELFPQKVRGPASGLTVAVGMFISFVVLKTY 450
            :.:::   |:.|..::|.|....:|...|||.:..|||.|..|..|..:...:....:|.|...:
Frog   373 VPVMR---YVSVACVIGIIAGFCIGPAGLPFIITGELFTQSHRPAAFIVGGTLNWLSNFTVGFVF 434

  Fly   451 PGIKEYLGMSNCFIIFGVMALFALIFVYLALPETRRRTLLEIEEQFRSGRSKSQNQA---DVEMK 512
            |.::...| :.|:::|..:.||...:||..:|||:.||.:||...|.|.:|...::.   |::::
Frog   435 PFLQISAG-AFCYMVFCGICLFVAAYVYYIIPETKNRTFMEISLMFSSSKSPVTHEVTADDLKLR 498

  Fly   513 EV 514
            .:
Frog   499 RL 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	110/417 (26%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	118/434 (27%)
slc2a9	XP_002936818.2	MFS_GLUT_Class2	30..475	CDD:340990	116/430 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910