DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8249 and Slc2a7

DIOPT Version :9

Sequence 1:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	XP_038967504.1	Gene:	Slc2a7 / 100362644	RGDID:	1583902	Length:	525	Species:	Rattus norvegicus

Alignment Length:	538	Identity:	143/538 - (26%)
Similarity:	236/538 - (43%)	Gaps:	86/538 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 PPPGEQTRAVRRQVIAVILANVG-VFSTGMTLAMPTATLHQLKDTT--EPV------HLNDSQAS 88
            |.|..:.|.....|:..:.|..| .|..|..:|: ..|.|::..::  .||      ..||:...
  Rat    11 PSPHMEARLQPTLVLTTLSAAFGSAFQYGYNIAV-INTPHKVGTSSGWGPVFQVLKSFYNDTYFE 74

  Fly    89 --------------WFASVNALSAPIGGLLS----GFLLDRIGRKKSLIVLNVLIILAWILLATP 135
                          |..:|:..  |:||||.    |.::::.|||::|::.||..|.:.:|:..
  Rat    75 RHGTFMDENTLLLLWSCTVSMF--PLGGLLGSLVVGMMVNKWGRKRTLLINNVFAITSAVLMGA- 136

  Fly   136 SESDQNAFFWQLIVSRFMLGVGMGLASAPPGVYAAEISVPKTRGSLILGTSISVAGGI------- 193
              |.....|..:|.||.|:|:..|:|.:...:|..|::....||:|...|.:.|..|:
  Rat   137 --SKAARAFELIIFSRVMVGICAGIAYSTLPMYLGELAPQNLRGTLGTMTEVFVIFGVLLAQIFS 199

  Fly   194 --TIL-YGIGYCIRDDFRLIALICCGYQLVALLCVLP-LPESHCWLLSKKRVTEAKR-SLNYFRG 253
              ||| ...|:.|     |:||  .|...:..|..|| .|||..:.|.:|...|..| :|...||
  Rat   200 LQTILGNATGWPI-----LLAL--TGVPALIQLLSLPFFPESPRYTLIEKGDEETTRQALRRLRG 257

  Fly   254 --FNKSDEITHPQVLEEFQLLQKSLQQRNTAVKESFWRNLHEPEVYKP----LVILMSLFAFQQL 312
              :|...|:...:..|..:..:..|...|..             .::|    |:.::.|.|.|||
  Rat   258 HSYNVEAEMEEMRTEERTEKAEGRLSVLNLF-------------TFRPLRWQLISIVVLMAGQQL 309

  Fly   313 TGIFVVIVFAVQISQEAGIEIDPFMCAVLI---GLARLITTCPMGYILEWWGRRRAGIISTLGM- 373
            :||..|..:|..|...||  :||.....:.   |:..|:.|....:|:|..|||.. ::|..|:
  Rat   310 SGINAVNYYADIIYTSAG--VDPTQSQYVTLGSGVINLVMTLVSAFIIERLGRRIL-LLSGYGIC 371

  Fly   374 -SVCMFLLAGHSQIEILKEVPYLPVVAIVGFIVLSTLGLYTLPFFMISELFPQKVRGPASGLTVA 437
             |.|:.|.........:.|:.||.::.:..:||..::|...:|..:.:|:..|..|..|..:..|
  Rat   372 GSACLVLTVALLLQSTVPELSYLGIICVFSYIVGHSIGPSPVPSVVRTEIVLQSSRTAAFTVDGA 436

  Fly   438 VGMFISFVVLKTYPGIKEYLGMSNCFIIFGVMALFALIFVYLALPETRRRTLLEIEEQFRSGRSK 502
            |....:|:|..|:|.|:..:| :..|:||..:.|....::|:.:|||:.:|.:||...|     .
  Rat   437 VHWLTNFIVGLTFPSIQVAIG-AYSFLIFAGICLLTAAYIYVVIPETKGKTFVEINCIF-----A 495

  Fly   503 SQNQADV-EMKEVFVRKP 519
            .:|..:| |.|||...||
  Rat   496 KRNGVEVSEEKEVTTAKP 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	123/479 (26%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	127/484 (26%)
Slc2a7	XP_038967504.1	MFS_GLUT_Class2	26..490	CDD:340990	128/493 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337733
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840