Protein Alignment CG8249 and slc2a5

DIOPT Version :10

• Sequence 1: NP_611060.2
• Gene: CG8249 / 36742
• FlyBaseID: FBgn0034045
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001352581.1
• Gene: slc2a5 / 100006415
• ZFINID: ZDB-GENE-060222-2
• Length: 511
• Species: Danio rerio
• Alignment Length: 538
• Identity: 131/538 - (24%)
• Similarity: 244/538 - (45%)
• Gaps: 68/538 - (12%)

  Fly     1 MDEQHQNLNQNGSESNGKQARIVSGLDRLLKTPPPGEQTRAVRRQVIAVILANVG-VFSTGMTLA 64
            |||:   :|....|..||...|::.                      |.::|..| .|..|..:|
Zfish     1 MDEE---VNMKKGERKGKVTLILAA----------------------ASLVAGFGSSFQYGYNVA 40

  Fly    65 MPTATLHQLKDTTEPVH------LNDSQASWFASVNALSAPIGG----LLSGFLLDRIGRKKSLI 119
            :..:...:::.....::      ::|:..:...||.....|:||    |:...|:::.|||.:|:
Zfish    41 VVNSPAPEMQQFYRRIYVDRYGPMSDNLLTLLWSVTVSMYPLGGFFGSLMVAPLVNKFGRKGTLL 105

  Fly   120 VLNVLIILAWILLATPSESDQNAFFWQLIVSRFMLGVGMGLASAPPGVYAAEISVPKTRGSLILG 184
            ..|:..|:..|::..   |:....|..:||:||::|:..||:|....:|..||:....||::.:.
Zfish   106 FNNIFSIVPAIMMGV---SEVAGSFEIIIVARFLVGICAGLSSNVVPMYLGEIAPKNYRGAVGIV 167

  Fly   185 TSISVAGGITI--LYGIGYCI-RDDFRLIALICCGYQLVALLCVLP-LPESHCWLLSKKRVTE-A 244
            ..:.:..||.:  ::||...: ..:...|.|...|......|.:|| .|||..::|.:|...: |
Zfish   168 PQLFITVGILVAQIFGIRSILGNKEGWPIMLGLTGIPAAIELLLLPFFPESPRYMLIQKGDEKTA 232

  Fly   245 KRSLNYFRGFNKSD-EITHPQVLEEFQLLQKSLQQRNTAVKESF-WRNLHEPEVYKPLVILMSLF 307
            ::.|...||....| |:...:|.|:.:..:..|...|.....|. |:.|.        ||.|::
Zfish   233 RKGLQRLRGCEDVDEELCEMRVEEQSERAEGRLSLLNLFTFRSLRWQLLS--------VIFMNM- 288

  Fly   308 AFQQLTGIFVVIVFAVQISQEAGIEIDPFM-CAVLIGLARLITTCPMGYILEWWGRRRAGIISTL 371
             .|||:|:..:..:|..|...||:..|... ..|..|...:..|....:|:|..||:   ::..:
Zfish   289 -GQQLSGVNAIYYYADSIYSSAGVSEDHVQYVTVGTGAVNVFMTITAVFIVEKSGRK---LLLLI 349

  Fly   372 GMSVC-----MFLLAGHSQIEILKEVPYLPVVAIVGFIVLSTLGLYTLPFFMISELFPQKVRGPA 431
            |..:|     :..:|.:.| ..|..:||:.:|.::.:::...:|...:|..:.:|:|.|..|.||
Zfish   350 GFGICCAACVILTIALYFQ-TTLDWIPYVSIVCVIVYVIGHAIGPSPIPTVITTEMFRQSSRPPA 413

  Fly   432 SGLTVAVGMFISFVVLKTYPGIKEYLGMSNCFIIFGVMALFALIFVYLALPETRRRTLLEIEEQF 496
            ..:..:|....:|.|...:|.::..||..: ||||..:.|..||::::.:|||:.:|.||..:.|
Zfish   414 FMVAGSVHWLSNFTVGLVFPFLERGLGPYS-FIIFACICLATLIYIWIVIPETKNKTFLETSKLF 477

  Fly   497 RSGRSKSQNQADVEMKEV 514
             :.|:|.:..|:....|:
Zfish   478 -AQRNKVEIMAEASDSEI 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8249	NP_611060.2	MFS_GLUT6_8_Class3_like	46..491	CDD:340916	116/468 (25%)
slc2a5	NP_001352581.1	MFS_GLUT_Class2	23..472	CDD:340990	116/466 (25%)