Protein Alignment Poxn and RHOXF2

DIOPT Version :10

• Sequence 1: NP_476686.1
• Gene: Poxn / 36741
• FlyBaseID: FBgn0003130
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: NP_115887.1
• Gene: RHOXF2 / 84528
• HGNCID: 30011
• Length: 288
• Species: Homo sapiens
• Alignment Length: 179
• Identity: 31/179 - (17%)
• Similarity: 53/179 - (29%)
• Gaps: 59/179 - (32%)

  Fly    68 RP-GSIGGSKTKQVATPTVVKKIIRLKEENSGMFAWEIREQLQQQRVCDPSSVPSISSINRILRN 131
            || |::||.:......|.|              .|:...:..:.:|:......||.....|:.|:
Human   120 RPQGAVGGLEPGNAQQPNV--------------HAFTPLQLQELERIFQREQFPSEFLRRRLARS 170

  Fly   132 SG-------LWTDEMTSSQQNAAAAAAAAAAAAHQAGSGPSNGYGGQAPPPPVTVA--------- 180
            ..       :|.:...:..:....|..|.......|...|......:|...|:.::
Human   171 MNVTELAVQIWFENRRAKWRRHQRALMARNMLPFMAVGQPVMVTAAEAITAPLFISGMRDDYFWD 235

  Fly   181 -----------PPTPAATPSIARYAKPPALMMNSAGEMPIKPAPKMPPS 218
                       ||.|           ||:|      .:|:...|.|||:
Human   236 HSHSSSLCFPMPPFP-----------PPSL------PLPLMLLPPMPPA 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Poxn	NP_476686.1	HTH_ARSR	5..133	CDD:481197	13/65 (20%)
RHOXF2	NP_115887.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	16..136		5/15 (33%)
		Homeodomain	139..191	CDD:459649	7/51 (14%)
		PRK02287	<183..>232	CDD:235024	6/48 (13%)
		Nuclear localization signal. /evidence=ECO:0000250	186..195		0/8 (0%)