Protein Alignment Poxn and Pax8

DIOPT Version :9

• Sequence 1: NP_001261016.1
• Gene: Poxn / 36741
• FlyBaseID: FBgn0003130
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: NP_112403.2
• Gene: Pax8 / 81819
• RGDID: 620434
• Length: 457
• Species: Rattus norvegicus
• Alignment Length: 489
• Identity: 169/489 - (34%)
• Similarity: 217/489 - (44%)
• Gaps: 131/489 - (26%)

  Fly     1 MPH----TGQAGVNQLGGVFVNGRPLPDCVRRRIVDLALCGVRPCDISRQLLVSHGCVSKILTRF 61
            |||    :|..|:|||||.||||||||:.||:||||||..|||||||||||.||||||||||.|:
  Rat     1 MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRY 65

  Fly    62 YETGSIRPGSIGGSKTKQVATPTVVKKIIRLKEENSGMFAWEIREQLQQQRVCDPSSVPSISSIN 126
            |||||||||.|||||.| ||||.||:||...|.:|..|||||||::|..:.|||..:|||:||||
  Rat    66 YETGSIRPGVIGGSKPK-VATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSIN 129

  Fly   127 RILRNS-----GLWTDEMTSSQQ--------NAAAAAAAAAAAAHQAGSGPS-NGYGGQAPP--- 174
            ||:|..     .|..|...:::.        .::|.....:..:...||..| ||..|.|.|
  Rat   130 RIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLGIAQPGSD 194

  Fly   175 -------------------PPVTVAPPTPAATPSIAR------------------YAKPPALMMN 202
                               ...:..|.....|.:..:                  ||.|    .:
  Rat   195 NKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDTFGQHHLEPLECPFERQHYPEAYASP----SH 255

  Fly   203 SAGEMPIKPAPKMPPSMGHGHSHGLNPNVSGL---------------------------DLSYSA 240
            :.||..:.|.|.:..::..|.: .|.|:.:.|                           :||.|:
  Rat   256 TKGEQGLYPLPLLNSTLDDGKA-TLTPSNTPLGRNLSTHQTYPVVADPHSPYAIKQETPELSSSS 319

  Fly   241 LHKHWLWNPSLLYYTQAHIQAQAAASGGQFLPYAGGYLP--HAMAAAAASSTSALGGFTKSE--S 301
            .      .||.| .:.|.:..|...|||.    ||..:|  :|.:.||    |..|.||...  |
  Rat   320 S------TPSSL-SSSAFLDLQQVGSGGP----AGASVPPFNAFSHAA----SVYGQFTGQALLS 369

  Fly   302 SIDLSTPGAAGDALSDCDSGKSSPAALSLTASGGGNGAGSAPEASPGSTLSHSRKRNPY-SIEEL 365
            ..::..|...|.......||:.|.|:.::    .|..|||  |.| |:..||:    || |..|.
  Rat   370 GREMVGPTLPGYPPHIPTSGQGSYASSAI----AGMVAGS--EYS-GNAYSHT----PYASYSEA 423

  Fly   366 LKKPEKRLRLDSNRLECLESSSCESSQDSPVAPP 399
            .:.|...|         |.|....||...|.|||
  Rat   424 WRFPNSSL---------LSSPYYYSSTTRPSAPP 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Poxn	NP_001261016.1	HTH	5..133	CDD:304362	91/132 (69%)
Pax8	NP_112403.2	PAX	9..133	CDD:128645	90/124 (73%)
		PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	12..68		45/55 (82%)
		RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	87..135		27/47 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	159..226		10/66 (15%)
		Pax2_C	344..455	CDD:289189	38/129 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810