Protein Alignment Poxn and PAX7

DIOPT Version :9

• Sequence 1: NP_001261016.1
• Gene: Poxn / 36741
• FlyBaseID: FBgn0003130
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: NP_002575.1
• Gene: PAX7 / 5081
• HGNCID: 8621
• Length: 520
• Species: Homo sapiens
• Alignment Length: 507
• Identity: 149/507 - (29%)
• Similarity: 197/507 - (38%)
• Gaps: 163/507 - (32%)

  Fly     5 GQAGVNQLGGVFVNGRPLPDCVRRRIVDLALCGVRPCDISRQLLVSHGCVSKILTRFYETGSIRP 69
            ||..||||||||:||||||:.:|.:||::|..|:|||.|||||.||||||||||.|:.|||||||
Human    34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRP 98

  Fly    70 GSIGGSKTKQVATPTVVKKIIRLKEENSGMFAWEIREQLQQQRVCDPSSVPS--ISSINRILR-- 130
            |:|||||.:|||||.|.|||...|.||.|||:||||::|.:...||.|:|||  :|||:|:||
Human    99 GAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIK 163

  Fly   131 ------------------------------NSGLWTDE-----------MTSSQQNAAAAAAA-- 152
                                          :.|...||           :...|:.:.....|
Human   164 FGKKEEEDEADKKEDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQ 228

  Fly   153 ------AAAAAH----------------------------------QAGSGPSNGYG----GQAP 173
                  |....|                                  |||:.....:.    |..|
Human   229 LEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFP 293

  Fly   174 PPPVTVAPP--TPAATPSIARYAKPPALMMNSAGEMPIKPAPKMPPSMGHGHSHGLNPNVSGLDL 236
            |..:...||  .|.:|       .|...:....|....:|.|..|.:|   |..||....:..|.
Human   294 PTGMPTLPPYQLPDST-------YPTTTISQDGGSTVHRPQPLPPSTM---HQGGLAAAAAAADT 348

  Fly   237 S--YSALHKHWLWNPSLLYYTQAHIQAQAAASGGQFLPYAGGYLPHAMAAAAASSTSALGGFTKS 299
            |  |.|.|....::.|.:         ..||......|.:.|..|..|:.
Human   349 SSAYGARHSFSSYSDSFM---------NPAAPSNHMNPVSNGLSPQVMSI--------------- 389

  Fly   300 ESSIDLSTPGA------AGDALSDCDSGKSSPAALSLTASGGGNGAGSAPEASPGSTLSHSRKRN 358
                 |..|.|      |..::|....|..|..::|.:.|      ..|....||.:|..|:...
Human   390 -----LGNPSAVPPQPQADFSISPLHGGLDSATSISASCS------QRADSIKPGDSLPTSQAYC 443

  Fly   359 P-------YSIEELLKKPEKRLRLDSNRLECLESSSCESSQDSPVAPPLETP 403
            |       ||::.:......:.    .:.|||...:      |||..|..||
Human   444 PPTYSTTGYSVDPVAGYQYGQY----GQSECLVPWA------SPVPIPSPTP 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Poxn	NP_001261016.1	HTH	5..133	CDD:304362	85/161 (53%)
PAX7	NP_002575.1	paired box domain	34..164		85/129 (66%)
		PAX	34..163	CDD:238076	85/128 (66%)
		octapeptide	86..93		3/6 (50%)
		paired homeodomain	217..275		4/57 (7%)
		Homeobox	220..273	CDD:278475	3/52 (6%)
		Pax7	347..385	CDD:289156	10/46 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	389..409		5/39 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810