Protein Alignment Poxn and PAX4

DIOPT Version :9

• Sequence 1: NP_001261016.1
• Gene: Poxn / 36741
• FlyBaseID: FBgn0003130
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: NP_001353039.1
• Gene: PAX4 / 5078
• HGNCID: 8618
• Length: 351
• Species: Homo sapiens
• Alignment Length: 363
• Identity: 114/363 - (31%)
• Similarity: 153/363 - (42%)
• Gaps: 108/363 - (29%)

  Fly     1 MPHTGQAGVNQLGGVFVNGRPLPDCVRRRIVDLALCGVRPCDISRQLLVSHGCVSKILTRFYETG 65
            |...|.:.:|||||:||||||||...|::||.||:.|:|||||||.|.||:|||||||.|:|.||
Human     1 MHQDGISSMNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTG 65

  Fly    66 SIRPGSIGGSKTKQVATPTVVKKIIRLKEENSGMFAWEIREQLQQQRVCDPSSVPSISSINRILR 130
            .:.|..|||||.: :|||.||.:|.:||.|...:|||||:.||..:.:|.....||:|||||:||
Human    66 VLEPKGIGGSKPR-LATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSVSSINRVLR 129

  Fly   131 NSGLWTDE-MTSSQQNAAAAAAAAAAAAHQA-----GSGPSNGY-------------------GG 170
              .|..|: :..::..:.|..|.|....|..     |:.|..|:                   .|
Human   130 --ALQEDQGLPCTRLRSPAVLAPAVLTPHSGSETPRGTHPGTGHRNRTIFSPSQAEALEKEFQRG 192

  Fly   171 QAP------------------------------------------------------PPPVTVAP 181
            |.|                                                      .|.:..|.
Human   193 QYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQLPGASQGLTVPRVAPGIISAQ 257

  Fly   182 PTPAATPSIARYAKPP------ALMMNSAGEMPIKPAPK---MPPSMGHGHSHGLNPNVSGLDLS 237
            .:|.:.|:.|..|..|      .|...:|.|..:...|.   :.|..||     |.|..:.||..
Human   258 QSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKACLKPCWGH-----LPPQPNSLDSG 317

  Fly   238 YSALHKHWLWNPSLLYYTQAHIQAQAAASGGQFLPYAG 275
            ...|.     .||    :..|:   |:.||.|.|.:.|
Human   318 LLCLP-----CPS----SHCHL---ASLSGSQALLWPG 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Poxn	NP_001261016.1	HTH	5..133	CDD:304362	73/127 (57%)
PAX4	NP_001353039.1	PAX	5..129	CDD:128645	71/124 (57%)
		Homeobox	174..226	CDD:306543	3/51 (6%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910