DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Poxn and sv

DIOPT Version :9

Sequence 1:	NP_001261016.1	Gene:	Poxn / 36741	FlyBaseID:	FBgn0003130	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_524633.3	Gene:	sv / 43825	FlyBaseID:	FBgn0005561	Length:	844	Species:	Drosophila melanogaster

Alignment Length:	495	Identity:	160/495 - (32%)
Similarity:	206/495 - (41%)	Gaps:	102/495 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 GQAGVNQLGGVFVNGRPLPDCVRRRIVDLALCGVRPCDISRQLLVSHGCVSKILTRFYETGSIRP 69
            |..|||||||||||||||||.||:|||:||..|||||||||||.||||||||||:|:|||||.:.
  Fly   175 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCVSKILSRYYETGSFKA 239

  Fly    70 GSIGGSKTKQVATPTVVKKIIRLKEENSGMFAWEIREQLQQQRVCDPSSVPSISSINRILRNSGL 134
            |.|||||.| ||||.||..|...|.||..|||||||::|..:.:|...:|||:||||||:||.
  Fly   240 GVIGGSKPK-VATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVPSVSSINRIVRNK-- 301

  Fly   135 WTDEMTSSQQNAAAAAAAAAAAAHQAGSGPSNGYGGQAPPPPV-----TVAPPTPAATPSIARYA 194
                         ||..|.....||......:..||......|     |:..|.|..:.|.|...
  Fly   302 -------------AAEKAKHVHHHQQHHVSQSLGGGHIATESVDSSTGTIGEPQPPTSNSSANSV 353

  Fly   195 KPPALMMNSA-GEMPIKPAPKMPPSMGH---------------------------------GHSH 225
            ........|. ..:|......:..|:||                                 .|||
  Fly   354 NTNVSASASVHASIPTSGTDSVQVSVGHINANSNETTHINSTAEQRTTGYSINGILGIQHGHHSH 418

  Fly   226 GLNPN--VSGLDLSYSALHKHWLWNPSLLYYTQAHI-------QAQAAASGGQFLP--YAGGYL- 278
            ..|.|  |:..:.:.|:..:..:......:.|..|.       |..:..||.|...  ::|.:.
  Fly   419 NNNNNSSVNNNNNTESSCKRKRIEAHDENHDTNIHSDNDDGKRQRMSTYSGDQLYTNIWSGKWCI 483

  Fly   279 --PHAMAAAAASSTSALGG--FTKSESSIDLSTPGAAG--------------DALSDCDSGKSSP 325
              .|.:.|...:.|::.|.  .|..|:|...||...:|              |:::.....:||
  Fly   484 KDDHKLLAELGNLTASTGNCPATYYEASNGFSTTPISGSGATASGNDTSMLYDSITTISQTQSS- 547

  Fly   326 AALSLTASGGGNGAGSAPEASPGSTLSHSRKRNPYSIEELLKKP-EKRLRLDSNRLECLESSSCE 389
              :...|.|...|.||.....|.|  .|..|.:..||:|....| ...|..|.|........:|.
  Fly   548 --IYTPAIGPSIGTGSLTPLVPIS--MHEMKLSANSIQEQTVPPFYTALAFDGNYTSMTSLENCS 608

  Fly   390 S-----------SQDSPVAPPLETPEDEDPAEAEEEQEEE 418
            |           |.||....|:.|....|..|....:.:|
  Fly   609 SLVGQEHIVMPESSDSNTLCPISTRIVPDITETNSTRVKE 648

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Poxn	NP_001261016.1	HTH	5..133	CDD:304362	89/127 (70%)
sv	NP_524633.3	PAX	175..299	CDD:128645	87/124 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451038
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45636
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840