DRSC/TRiP Functional Genomics Resources

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Protein Alignment Poxn and Pax9

DIOPT Version :9

Sequence 1:NP_001261016.1 Gene:Poxn / 36741 FlyBaseID:FBgn0003130 Length:425 Species:Drosophila melanogaster
Sequence 2:NP_001034628.1 Gene:Pax9 / 362741 RGDID:1560838 Length:342 Species:Rattus norvegicus


Alignment Length:357 Identity:134/357 - (37%)
Similarity:170/357 - (47%) Gaps:64/357 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 PHTGQAGVNQLGGVFVNGRPLPDCVRRRIVDLALCGVRPCDISRQLLVSHGCVSKILTRFYETGS 66
            |..|:  |||||||||||||||:.:|.|||:||..|:|||||||||.||||||||||.|:.||||
  Rat     3 PAFGE--VNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGS 65

  Fly    67 IRPGSIGGSKTKQVATPTVVKKIIRLKEENSGMFAWEIREQLQQQRVCDPSSVPSISSINRILRN 131
            |.||:|||||.: |.||||||.|...|:.:.|:||||||::|....|||..:|||:|||:|||||
  Rat    66 ILPGAIGGSKPR-VTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRN 129

  Fly   132 S-GLWTDEMTSSQQNAAAAAAAAAAAAHQAGSGPSNGYGG-QAPPPPVTVAP---PTPAATPSIA 191
            . |           |.|......:...||....|:..|.. .:.|.|:|.|.   |||...|:| 
  Rat   130 KIG-----------NLAQQGHYDSYKQHQPAPQPALPYNHIYSYPSPITAAAAKVPTPPGVPAI- 182

  Fly   192 RYAKPPALMMNSAGEMPIKPAPKMPPSMGHGHSHGL----------NPNVSGLDLSYSALHKHWL 246
                |.::.:           |:..||     ||.:          :..||.....:|...:.| 
  Rat   183 ----PGSVAL-----------PRTWPS-----SHSVTDILGIRSITDQGVSDSSPYHSPKVEEW- 226

  Fly   247 WNPSLLYYTQAHIQAQAAASGGQFLPYAGGYLPHAMAAAAASSTSALGGFTKSESSIDLSTPGAA 311
               |.|........|..|.:|.:    .|.....|....|.:...|:..|..:.|.....||...
  Rat   227 ---SSLGRNNFSAAAPHAVNGLE----KGALEQEAKYGQAPNGLPAVSSFVSASSMAPYPTPAQV 284

  Fly   312 GDALSDCDSGKSSPAALSLTASGGGNGAGSAP 343
            ...::      .|.|.....|..|...|||.|
  Rat   285 SPYMT------YSAAPSGYVAGHGWQHAGSTP 310

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PoxnNP_001261016.1 HTH 5..133 CDD:304362 86/128 (67%)
Pax9NP_001034628.1 PAX 6..131 CDD:238076 86/127 (68%)
PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381 7..63 42/57 (74%)
RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381 82..130 27/47 (57%)
Interaction with KDM5B. /evidence=ECO:0000250 168..189 7/36 (19%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45636
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
33.010

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