Protein Alignment Poxn and pax2a

DIOPT Version :10

• Sequence 1: NP_476686.1
• Gene: Poxn / 36741
• FlyBaseID: FBgn0003130
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: XP_021336170.1
• Gene: pax2a / 30425
• ZFINID: ZDB-GENE-990415-8
• Length: 504
• Species: Danio rerio
• Alignment Length: 472
• Identity: 164/472 - (34%)
• Similarity: 203/472 - (43%)
• Gaps: 137/472 - (29%)

  Fly     1 MPHTGQAGVNQLGGVFVNGRPLPDCVRRRIVDLALCGVRPCDISRQLLVSHGCVSKI-------L 58
            :.|.|..|||||||||||||||||.||:|||:||..|||||||||||.|||||||||       |
Zfish    15 LSHIGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGSYQKDL 79

  Fly    59 TRFYETGSIRPGSIGGSKTKQVATPTVVKKIIRLKEENSGMFAWEIREQLQQQRVCDPSSVPSIS 123
            .|:||||||:||.|||||.| ||||.||:||...|.:|..|||||||::|..:.|||..:|||:|
Zfish    80 IRYYETGSIKPGVIGGSKPK-VATPKVVEKIAEYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVS 143

  Fly   124 SINRILRNSGLWTDEMTSSQQ----NAAAAAAAAAAAAHQAGSGPSNGYG---GQAPPPPVTVAP 181
            |||||:|         |..||    ::.......:.|.|..|...|..|.   ..|...|.|.:|
Zfish   144 SINRIIR---------TKVQQPFHPSSDGTGTPLSTAGHTIGDLESTPYTLTYSCALSVPSTASP 199

  Fly   182 P-TPAATPSIARYAKPPALMMNSAGEMPIKPAPKMP-------------PSMGHGHSHGLNPNVS 232
            | :.|:...:..|:      :|....:|.....|..             ..:|:..|.|..|| |
Zfish   200 PVSSASNDPVGSYS------INGILGIPRSNGEKRKRDDVLWSGNHLDGRKIGYYGSDGSGPN-S 257

  Fly   233 GLDLSYSALHKHW----------------LWNPSL--LYYTQAHIQAQAAASGGQFLPYAGGYLP 279
            ....|..:|.||.                ...||.  ::.|..||:.:.|  ....||.....|.
Zfish   258 DSQGSVESLRKHLRADAFTQQQLEALDRVFERPSYPDVFPTSEHIKPEQA--NEYSLPALNPGLD 320

  Fly   280 HAMAAAAASSTSALGG--------FTKSES----------------------------------- 301
            ....:.:.|.:|.||.        .|:|.|
Zfish   321 EVKPSLSTSVSSDLGSSVSQSYPVVTESHSSSMCVKQEPHEASLAPFTPSSLAVSGLAELLPLQP 385

  Fly   302 --SIDLSTP--GA-AGDALSDCD-------SGKSSPAALSLTASG-----GGNGAGSAPEAS--- 346
              |:|.|||  || |..|.|.|.       :|:.   ..|.|..|     ...|.||.|.::
Zfish   386 SVSVDASTPCYGAYAHHAPSYCQYTSQHIIAGRE---MASTTLPGYPPHVPPTGQGSYPTSTLAG 447

  Fly   347 --PGSTLSHSRKRNPYS 361
              |||..|    .||||
Zfish   448 MVPGSDFS----GNPYS 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Poxn	NP_476686.1	HTH_ARSR	5..133	CDD:481197	92/134 (69%)
pax2a	XP_021336170.1	PAX	19..150	CDD:128645	91/131 (69%)
		Zinc_peptidase_like	<257..377	CDD:472712	21/121 (17%)
		Pax2_C	391..503	CDD:463563	25/77 (32%)