DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Poxn and Pax2

DIOPT Version :9

Sequence 1:	NP_001261016.1	Gene:	Poxn / 36741	FlyBaseID:	FBgn0003130	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	XP_006231505.2	Gene:	Pax2 / 293992	RGDID:	1305568	Length:	432	Species:	Rattus norvegicus

Alignment Length:	420	Identity:	152/420 - (36%)
Similarity:	188/420 - (44%)	Gaps:	121/420 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 HTGQAGVNQLGGVFVNGRPLPDCVRRRIVDLALCGVRPCDISRQLLVSHGCVSKILTRFYETGSI 67
            |.|..|||||||||||||||||.||:|||:||..|||||||||||.||||||||||.|:||||||
  Rat    14 HPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSI 78

  Fly    68 RPGSIGGSKTKQVATPTVVKKIIRLKEENSGMFAWEIREQLQQQRVCDPSSVPSISSINRILRNS 132
            :||.|||||.| ||||.||.||...|.:|..|||||||::|..:.:||..:|||:||||||:|
  Rat    79 KPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIR-- 140

  Fly   133 GLWTDEMTSSQQNAAAAAAAAAAAAHQAGSGPSNGYGGQAPPPPVTVAPPTPAATPSIARYAKPP 197
                   |..||           ..|....|...|    ...|..|:.|.|  |:|.::..:..|
  Rat   141 -------TKVQQ-----------PFHPTPDGAGTG----VTAPGHTIVPST--ASPPVSSASNDP 181

  Fly   198 ALMMNSAGEMPIKPAPKMPPSMGH-------------GH----------------SHGLNPN--- 230
                  .|...|.....:|.|.|.             .|                |.|..||
  Rat   182 ------VGSYSINGILGIPRSNGEKRKREEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDS 240

  Fly   231 VSGLDLSYSALHKHW----------------LWNPSL--LYYTQAHIQAQAAASGGQF-LPYAGG 276
            .||:|    :|.||.                ...||.  ::....||:::   .|.:: ||....
  Rat   241 QSGVD----SLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSE---QGNEYSLPALTP 298

  Fly   277 YLPHAMAAAAASSTSALGGFTKSESSIDLSTPGAAGDALSDCDSGKSSPAALSLTASG-----GG 336
            .|....::.:||:...||    |..|...:.|...|..::            |.|..|     ..
  Rat   299 GLDEVKSSLSASTNPELG----SNVSGTQTYPVVTGRDMA------------STTLPGYPPHVPP 347

  Fly   337 NGAGSAPEAS-----PGSTLSHSRKRNPYS 361
            .|.||.|.::     |||..|    .||||
  Rat   348 TGQGSYPTSTLAGMVPGSEFS----GNPYS 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Poxn	NP_001261016.1	HTH	5..133	CDD:304362	91/127 (72%)
Pax2	XP_006231505.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002430
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810