Protein Alignment Poxn and Pax5

DIOPT Version :9

• Sequence 1: NP_001261016.1
• Gene: Poxn / 36741
• FlyBaseID: FBgn0003130
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: NP_032808.1
• Gene: Pax5 / 18507
• MGIID: 97489
• Length: 391
• Species: Mus musculus
• Alignment Length: 411
• Identity: 149/411 - (36%)
• Similarity: 185/411 - (45%)
• Gaps: 131/411 - (31%)

  Fly     4 TGQAGVNQLGGVFVNGRPLPDCVRRRIVDLALCGVRPCDISRQLLVSHGCVSKILTRFYETGSIR 68
            ||..|||||||||||||||||.||:|||:||..|||||||||||.||||||||||.|:||||||:
Mouse    15 TGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIK 79

  Fly    69 PGSIGGSKTKQVATPTVVKKIIRLKEENSGMFAWEIREQLQQQRVCDPSSVPSISSINRILRNSG 133
            ||.|||||.| ||||.||:||...|.:|..|||||||::|..:||||..:|||:||||||:|
Mouse    80 PGVIGGSKPK-VATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIR--- 140

  Fly   134 LWTDEMTSSQQNAAAAAAAAAAAAHQAGSGPSNGYGGQAPPPPVTVAPPTPAATPSIARYAKPPA 198
                  |..|                           |.|..||..:..:..:|.|:.:.:   :
Mouse   141 ------TKVQ---------------------------QPPNQPVPASSHSIVSTGSVTQVS---S 169

  Fly   199 LMMNSAGE-----------MPIKPAPKMPPSMG-------HGHS----HGLNPNVSG-------- 233
            :..:|||.           .|.....|.....|       :|||    ..|...:.|
Mouse   170 VSTDSAGSSYSISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQL 234

  Fly   234 --LDLSYSALHKHWLWNPSLLYYTQAHIQAQAAASGGQFLPYAGGYLPHAMAAAAASSTSALGGF 296
              ||..:...|.      |.::.|...|:.:      |...|:      |||:.|       ||.
Mouse   235 EVLDRVFERQHY------SDIFTTTEPIKPE------QTTEYS------AMASLA-------GGL 274

  Fly   297 TKSESSIDLSTPGAAGDALSDCDSGKSSPA-----------ALSLTASG-------GGNGAGSAP 343
            ...::::...||         .|.|.|.|.           ..|.|..|       .|.|:.|||
Mouse   275 DDMKANLTSPTP---------ADIGSSVPGPQSYPIVTGRDLASTTLPGYPPHVPPAGQGSYSAP 330

  Fly   344 EAS---PGSTLSHSRKRNPYS 361
            ..:   |||..|.|    |||
Mouse   331 TLTGMVPGSEFSGS----PYS 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Poxn	NP_001261016.1	HTH	5..133	CDD:304362	93/127 (73%)
Pax5	NP_032808.1	PAX	16..140	CDD:128645	92/124 (74%)
		PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	19..75		47/55 (85%)
		RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	94..142		28/56 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	182..218		6/35 (17%)
		Pax2_C	285..389	CDD:289189	22/76 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002430
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810