Protein Alignment Poxn and Pax2

DIOPT Version :9

• Sequence 1: NP_001261016.1
• Gene: Poxn / 36741
• FlyBaseID: FBgn0003130
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: NP_001355672.1
• Gene: Pax2 / 18504
• MGIID: 97486
• Length: 432
• Species: Mus musculus
• Alignment Length: 420
• Identity: 152/420 - (36%)
• Similarity: 188/420 - (44%)
• Gaps: 121/420 - (28%)

  Fly     3 HTGQAGVNQLGGVFVNGRPLPDCVRRRIVDLALCGVRPCDISRQLLVSHGCVSKILTRFYETGSI 67
            |.|..|||||||||||||||||.||:|||:||..|||||||||||.||||||||||.|:||||||
Mouse    14 HPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSI 78

  Fly    68 RPGSIGGSKTKQVATPTVVKKIIRLKEENSGMFAWEIREQLQQQRVCDPSSVPSISSINRILRNS 132
            :||.|||||.| ||||.||.||...|.:|..|||||||::|..:.:||..:|||:||||||:|
Mouse    79 KPGVIGGSKPK-VATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIR-- 140

  Fly   133 GLWTDEMTSSQQNAAAAAAAAAAAAHQAGSGPSNGYGGQAPPPPVTVAPPTPAATPSIARYAKPP 197
                   |..||           ..|....|...|    ...|..|:.|.|  |:|.::..:..|
Mouse   141 -------TKVQQ-----------PFHPTPDGAGTG----VTAPGHTIVPST--ASPPVSSASNDP 181

  Fly   198 ALMMNSAGEMPIKPAPKMPPSMGH-------------GH----------------SHGLNPN--- 230
                  .|...|.....:|.|.|.             .|                |.|..||
Mouse   182 ------VGSYSINGILGIPRSNGEKRKREEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDS 240

  Fly   231 VSGLDLSYSALHKHW----------------LWNPSL--LYYTQAHIQAQAAASGGQF-LPYAGG 276
            .||:|    :|.||.                ...||.  ::....||:::   .|.:: ||....
Mouse   241 QSGVD----SLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSE---QGNEYSLPALTP 298

  Fly   277 YLPHAMAAAAASSTSALGGFTKSESSIDLSTPGAAGDALSDCDSGKSSPAALSLTASG-----GG 336
            .|....::.:||:...||    |..|...:.|...|..::            |.|..|     ..
Mouse   299 GLDEVKSSLSASANPELG----SNVSGTQTYPVVTGRDMT------------STTLPGYPPHVPP 347

  Fly   337 NGAGSAPEAS-----PGSTLSHSRKRNPYS 361
            .|.||.|.::     |||..|    .||||
Mouse   348 TGQGSYPTSTLAGMVPGSEFS----GNPYS 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Poxn	NP_001261016.1	HTH	5..133	CDD:304362	91/127 (72%)
Pax2	NP_001355672.1	PAX	16..140	CDD:128645	90/124 (73%)
		PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	19..75		47/55 (85%)
		RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	94..142		26/56 (46%)
		homeodomain	255..>278	CDD:381795	2/22 (9%)
		Pax2_C	305..>390	CDD:372091	23/89 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002430
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810