DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Poxn and egl-38

DIOPT Version :9

Sequence 1:	NP_001261016.1	Gene:	Poxn / 36741	FlyBaseID:	FBgn0003130	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_501836.1	Gene:	egl-38 / 177876	WormBaseID:	WBGene00001204	Length:	289	Species:	Caenorhabditis elegans

Alignment Length:	259	Identity:	111/259 - (42%)
Similarity:	146/259 - (56%)	Gaps:	30/259 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 HTGQAGVNQLGGVFVNGRPLPDCVRRRIVDLALCGVRPCDISRQLLVSHGCVSKILTRFYETGSI 67
            ||   |||||||||||||||.|.||.:||:::..|.|||||||||.||||||||||.|:|.|||:
Worm    30 HT---GVNQLGGVFVNGRPLADTVRAQIVEMSQHGTRPCDISRQLKVSHGCVSKILGRYYSTGSV 91

  Fly    68 RPGSIGGSKTKQVATPTVVKKIIRLKEENSGMFAWEIREQLQQQRVCDPSSVPSISSINRILRNS 132
            |||.|||||.| ||||.||:.|...|..|..|||||||::|.:.::|...:|||:||||||:||.
Worm    92 RPGVIGGSKPK-VATPRVVECIAGYKRANPTMFAWEIRQKLIEDQICGEENVPSVSSINRIVRNK 155

  Fly   133 GLWTDEMTSSQQNAAAAAAAAAAAAHQAGSGPSNGYGGQAPPPPVTVAPPTPAATPSIARYAKPP 197
            .........:...::||..::|.:.||           ::||..|........:...:.:.....
Worm   156 SFMAQLAAPTSVTSSAARPSSATSHHQ-----------RSPPRGVQQHMQQSTSVQQLQQLQLTS 209

  Fly   198 ALMMNSAGEMPIKPAPKMPPSMGHGHSHGLN------PNVSGLDLSYSALHKHWLWNPSLLYYT 255
            |..:||   :...||..||     |.::.:|      |..|.||..::.|..... :.||:|.|
Worm   210 AATVNS---LMTPPAFAMP-----GTAYSINGLLGTLPQPSLLDDKFTNLSTQSA-DMSLVYST 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Poxn	NP_001261016.1	HTH	5..133	CDD:304362	83/127 (65%)
egl-38	NP_501836.1	PAX	29..153	CDD:128645	83/126 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156318
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	176	1.000	Inparanoid score	I2695
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002430
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.790