Protein Alignment Poxn and Pax3

DIOPT Version :10

• Sequence 1: NP_476686.1
• Gene: Poxn / 36741
• FlyBaseID: FBgn0003130
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: NP_446162.1
• Gene: Pax3 / 114502
• RGDID: 620431
• Length: 484
• Species: Rattus norvegicus
• Alignment Length: 456
• Identity: 142/456 - (31%)
• Similarity: 204/456 - (44%)
• Gaps: 99/456 - (21%)

  Fly     5 GQAGVNQLGGVFVNGRPLPDCVRRRIVDLALCGVRPCDISRQLLVSHGCVSKILTRFYETGSIRP 69
            ||..||||||||:||||||:.:|.:||::|..|:|||.|||||.||||||||||.|:.|||||||
  Rat    34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRP 98

  Fly    70 GSIGGSKTKQVATPTVVKKIIRLKEENSGMFAWEIREQLQQQRVCDPSSVPSISSINRILRNS-G 133
            |:|||||.|||.||.|.|||...|.||.|||:||||::|.:..|||.::|||:|||:||||:. |
  Rat    99 GAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFG 163

  Fly   134 LWTDEMTSSQQNAAAAAAAAA-----AAAHQAGSGPSNGYGGQAPPPPVTVAPPTPAATPSIARY 193
            ...:|....::..|..:...|     ....:..|.|.:..|..
  Rat   164 KGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSD---------------------- 206

  Fly   194 AKPPALMMNSAGEMPIKPAPKMPPSMGHGHSHGLNPNVSGLDLSYSALHKHWLWNPSLL----YY 254
                   ::|..::|:|...:      ...:......:..|:.::...|...::....|    ..
  Rat   207 -------IDSEPDLPLKRKQR------RSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKL 258

  Fly   255 TQAHIQA---------QAAASGGQFLPY----AGGYLPHAM--------------------AAAA 286
            |:|.:|.         :..|...|.:.:    .||:.|.||                    |.:.
  Rat   259 TEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVSD 323

  Fly   287 ASST----SALGGFTKSESSIDLSTPGAAGDALSDCDSGKSSPAALSLTASGGGN------GAGS 341
            .|||    ..|...|..:|:|..:...::...|.....|.||.....:..||..|      |.|.
  Rat   324 PSSTVHRPQPLPPSTVHQSTIPSNADSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPAIGNGL 388

  Fly   342 APEASPGSTLSHS----RKRNPYSIEELLKKPEKRLRLD---SNRLECLES-SSCESSQDSPVAP 398
            :|:.. |...:|.    :.:..|::..|....|....:.   |.|||.::: .|..:||  |..|
  Rat   389 SPQVM-GLLTNHGGVPHQPQTDYALSPLTGGLEPTTTVSASCSQRLEHMKNVDSLPTSQ--PYCP 450

  Fly   399 P 399
            |
  Rat   451 P 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Poxn	NP_476686.1	HTH_ARSR	5..133	CDD:481197	86/128 (67%)
Pax3	NP_446162.1	PAX	34..159	CDD:128645	84/124 (68%)
		Homeodomain	220..276	CDD:459649	6/61 (10%)
		Pax7	347..391	CDD:403540	9/43 (21%)