DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp52 and YHP1

DIOPT Version :9

Sequence 1:	NP_001027420.2	Gene:	Zasp52 / 36740	FlyBaseID:	FBgn0265991	Length:	2194	Species:	Drosophila melanogaster
Sequence 2:	NP_010739.3	Gene:	YHP1 / 852062	SGDID:	S000002859	Length:	353	Species:	Saccharomyces cerevisiae

Alignment Length:	311	Identity:	71/311 - (22%)
Similarity:	113/311 - (36%)	Gaps:	50/311 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly  1407 RNWTVLPTQSPIRTPEPQELRENVPLAFVDAPKAPVTSDSSTVHRPIAQVAAPTTVVAPSREREK 1471
            || ||||:...|.|.     ..|.|......|.....||.....| :..:||...:|.|.....|
Yeast     4 RN-TVLPSLPNIITG-----TSNSPFQLHTLPNTNFPSDDQGDIR-LPPLAASAHIVRPVVNIYK 61

  Fly  1472 ----ERRPQLSVPIIVEDRSGPVTMAFQPLDELVRPDQALTPTRPYTPS--LTNKPAPIVPFYQT 1530
                |.||:...|..|:..|..||.:..||.:    .:.|:...|:||:  :.:|..|....:..
Yeast    62 SPCDEERPKRKSPQAVDFLSQRVTTSMTPLSK----PKKLSSHSPFTPTVRVCSKEQPPQSMHSY 122

  Fly  1531 EEKLVFEECSATHARNYNELNASPFPDRTRSPA---------PGPPPNPLNAIRAPRMKEPETKS 1586
            ::..:....||..|    .|..:...::.||.|         |...|...|| |..|.|...|.|
Yeast   123 KKVNILTPLSAAKA----VLTPTTRKEKKRSFAFITHSQETFPKKEPKIDNA-RLARRKRRRTSS 182

  Fly  1587 NILSVSGGPRLQTGSITTGQSYQGQLLAHSEQ--SSQSASQSYNQQPERITEQRVGNLN-----I 1644
            ..|.:     |||.........:.:.:..|||  .|:.:.|.:.|...:..::...:.|     :
Yeast   183 YELGI-----LQTAFDECPTPNKAKRIELSEQCNMSEKSVQIWFQNKRQAAKKHKNSGNTSHCKV 242

  Fly  1645 QQREQSSQLQQQAQSQTQSQTRSQVGNTQIERRRKVTEEFERTQSAKTIEI 1695
            ...:..|.:       :.|....::.:|....:..:|.|..:|..|.|..|
Yeast   243 HSNDSMSMI-------SYSDAALEITSTPTSTKEAITAELLKTSPANTSSI 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp52	NP_001027420.2	PDZ_signaling	6..87	CDD:238492
		DUF4749	150..>217	CDD:292558
		LIM_ALP_like	282..333	CDD:188746
		LIM1_Enigma_like_1	2020..2073	CDD:188839
		LIM	2081..2132	CDD:259829
		LIM3_Enigma_like_1	2140..2193	CDD:188845
YHP1	NP_010739.3	COG5576	123..278	CDD:227863	32/171 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030