DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp52 and mxtx2

DIOPT Version :9

Sequence 1:	NP_001027420.2	Gene:	Zasp52 / 36740	FlyBaseID:	FBgn0265991	Length:	2194	Species:	Drosophila melanogaster
Sequence 2:	NP_001073284.1	Gene:	mxtx2 / 58078	ZFINID:	ZDB-GENE-000710-6	Length:	296	Species:	Danio rerio

Alignment Length:	338	Identity:	65/338 - (19%)
Similarity:	110/338 - (32%)	Gaps:	107/338 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly  1667 SQVGNTQ---IERRRKVT----EEFERTQSAKTIEIRTGSQSVSQSKAQSQSISQAQTQAQSQSQ 1724
            :|.||:|   |..|||.|    |..|..:.|..::...|. ||.:|.:|:..:.:::.|...|::
Zfish    10 AQDGNSQASKIAGRRKRTSFTKEHLELLKMAFNVDPYPGI-SVRESLSQATGLPESRIQVWFQNK 73

  Fly  1725 NQSDTERRSSYGKTGFVASQAKRLSCMEEEISSLTSQSQAISARASALGEGCFPNLRSPTFDSKF 1789
            .                               :.|.:::||.:              ||..|:|.
Zfish    74 R-------------------------------ARTLKNRAIQS--------------SPQLDNKS 93

  Fly  1790 PLKPAPAESIVPGYATVPAATKMLTAPPPGF-LQQQQQQQQRSAF--SGYQATTSSVQQSSFASS 1851
            ||   |:..:.|..|:|..:.:........| :|..|...|...|  |.|.......:|:....:
Zfish    94 PL---PSPFLPPHMASVGVSAQQRGIQESPFNIQMSQTSPQHFTFPPSDYSTPVVKPRQTRLMGT 155

  Fly  1852 SKATTSSLSSSSASASASASVARSSQSLTQASAITTTTNNQATTAYRSSNGSITKPNLASRPSIA 1916
            |..:.|.|.::..|.|.:.|...|.:|...|:       .....:|:..:.....|
Zfish   156 SSCSPSDLQATPDSWSYAGSTQISPESWDVAA-------ENFGNSYKDESPFFLYP--------- 204

  Fly  1917 SITAPGSASAPAPVP---------------SAAPTKATAPF-------KAPIVPKSVIANAVNAA 1959
                      |.|.|               |.:|..:.:.|       .:|.||.:...:..:..
Zfish   205 ----------PPPYPYGSTRVGCPSSMESLSTSPASSDSAFWDMGLENCSPSVPYTSCGSPWDRL 259

  Fly  1960 APPAPAVFPPDLS 1972
            ....|....||||
Zfish   260 TEEQPVAPLPDLS 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp52	NP_001027420.2	PDZ_signaling	6..87	CDD:238492
		DUF4749	150..>217	CDD:292558
		LIM_ALP_like	282..333	CDD:188746
		LIM1_Enigma_like_1	2020..2073	CDD:188839
		LIM	2081..2132	CDD:259829
		LIM3_Enigma_like_1	2140..2193	CDD:188845
mxtx2	NP_001073284.1	HOX	22..76	CDD:197696	14/85 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.030