Protein Alignment Zasp52 and synpo2la

DIOPT Version :10

• Sequence 1: NP_001027420.2
• Gene: Zasp52 / 36740
• FlyBaseID: FBgn0265991
• Length: 2194
• Species: Drosophila melanogaster
• Sequence 2: XP_009305650.2
• Gene: synpo2la / 563843
• ZFINID: ZDB-GENE-090828-4
• Length: 1179
• Species: Danio rerio
• Alignment Length: 1565
• Identity: 278/1565 - (17%)
• Similarity: 447/1565 - (28%)
• Gaps: 580/1565 - (37%)

  Fly    18 PWGFRLQGGTDFAQPLLVQKVNAGSLSEQAGLQPGDAVVKINDVDVFNLRHKDAQDIVVRSGNNF 82
            |||||||||.:..:||.|.||...|.:.:|||:.||.::.||:....:|.|..|.:::.......
Zfish    15 PWGFRLQGGIEHQKPLQVAKVRKRSKACRAGLREGDELMSINENSCGSLSHAQAMNLIDSMPGTL 79

  Fly    83 VITVQRGGSTWRPHVTPTGNVPQPNSPYLQTVTKTSLAHKQQDSQHIGCGYNNAARPFSNGGDGG 147
            .|.|:|
Zfish    80 HIRVRR----------------------------------------------------------- 85

  Fly   148 VKSIVNKQYNTPVGIYSDESIAETLSAQAEVLAGGVLGVNFKKNEKEYQGDRSEVLKFLREEETG 212
                      .|.|..|...:|...|.:.               :|||:.       .||.....
Zfish    86 ----------APAGFQSVVLVARAPSPRI---------------DKEYRA-------ALRAMSPS 118

  Fly   213 QSTPAFGNSHYEHDAPQQLQQPQQQYNQHQQHYHQQQQQQQSSTTRHVSAPVNSPKPPSTGGLPT 277
            .|.|                        ||....|..:....|                    ||
Zfish   119 SSRP------------------------HQSSVRQIHRGTLMS--------------------PT 139

  Fly   278 GQNICTECERLITGVFVRIKDKNLHVECFKCATCGTSLKNQGYYNFNNKLYCDIHAKQAAINNPP 342
            |                                                        ::.:.:||
Zfish   140 G--------------------------------------------------------RSGLTSPP 148

  Fly   343 TGTEGYVPVPIKPNTKLSASTISSALNSHGYGGHSNGYSNGNSTPAPAPVASSQATATVATVAPS 407
             |:|.|                        ||          .|.:.|.||:.:........:||
Zfish   149 -GSEAY------------------------YG----------ETDSDADVAAHERHRKPKRRSPS 178

  Fly   408 AATAATAAATPQAATATDSPAATASSSDNMSAYVADEPSSIYGQI-------SAESVALAPPPPQ 465
            .:......|:|:.|..::           ||.|.:...:.:|..:       :...||......|
Zfish   179 NSPGKAGRASPEGAETSE-----------MSGYDSASDAQMYKLLGPNKREDTLPGVARREVIYQ 232

  Fly   466 PPTAGGGDQPFEYVTLTGNVIRSVQAPGKGACPSYKVNQGYARPFGAAAPKSPVSYPPQQQQQSP 530
            ||..|....  :..|.|.::....|.|.:|.   .:.:.|:         :.|.:.||....:..
Zfish   233 PPLHGAWSS--QTSTETSSMSADDQNPREGL---MEEDSGF---------QEPTNIPPLVSPERA 283

  Fly   531 RPAPGGQNPYATLPRSNVGQQGGEAVEELQPEFEEEDCYEMDIEVALAASRQSQRGSSFTWPPPQ 595
            :.|....:....:|.  ||.......|||...:.::           |...:..||.:.|....:
Zfish   284 KEALMLSSRSQLVPM--VGPVDNPVDEELTLTYMDK-----------AKQAKLNRGETITDKQVK 335

  Fly   596 DDSHLAPTAAPLY--IPPPETQHVV-------------------VSNPVQQVPPLPPG---GATA 636
            :......|.|.|.  .|.|.::.|:                   |...::|......|   |:.:
Zfish   336 EARSKCRTIASLLTDAPNPHSKGVLMFKKRRQRSKKYTLTSFGSVDEDMRQDSQEEDGIFPGSES 400

  Fly   637 RLDPQPVVGTSANGAPQWQSYSAPQL--TTASARQLAEQESSSDSYTSTSTTTTTTSEEYQRMYA 699
            ..|.:   |.||...|.|.|.....|  ..||..|..:..:.|...:.||              .
Zfish   401 EFDEE---GFSAAPDPTWDSDYLEMLEKRCASRGQEGDGGALSPGLSDTS--------------G 448

  Fly   700 AQVQAYQMQEQSGSEFDYQVDYASTQDSVQDYPSGRRSAQECVDS--LAVPLSTYKLVDMVREVT 762
            ...|.::.|.:...|...:::                :|||.:.|  |.:.|...:.:..::...
Zfish   449 KGAQLFEQQRKRAEEHARKIE----------------AAQEQLQSQMLGISLKEAQALPPLQTAH 497

  Fly   763 PSPVT-----TPTQTPAPAAPTTRRVVFND-----EPEIKELPQLPAELETIP-----EASEAVE 812
            |.|:|     .|...|.||.|:|  .:::|     ....|.....|..:.|:|     :||....
Zfish   498 PDPLTKLNVQPPPVAPKPARPST--TLYHDVQAAEAQNNKTQMNTPQTIPTVPVMVNGDASNTTV 560

  Fly   813 DREGLVIEQRCQILESERKFQPTPEIKIEIAPVRQIPPTKIPNPMPKEW---------------I 862
            ....::.:....:|.:|....|.|      .|:.::|.:.:.|...:.:               .
Zfish   561 TAPSVMPKTNLSVLSTETVMPPPP------TPLPELPASSVLNRTARPFAPGCITNRAATAPVVF 619

  Fly   863 NPMIRVLTTAPEVPFHLVECPFP----------RPCGDDFEAEAAAAEAAKTQEV--PEPLPPQV 915
            .|.:...|..| |...:|..|||          .|.....:...:...|..:.|:  .:||....
Zfish   620 RPAVSKKTPRP-VSVAVVAPPFPAASEEHVMCVTPAIFGTQVTMSQMNANVSNEIIPTQPLAQGT 683

  Fly   916 SAAPPATVSVEPSPAPLRESPPRGSRLSQAMVTAPEFELKFAPPADQGIPLPEETEPYMP----- 975
            |..|||.||||             |....|...:|...::.|     .:|..:..:|.:|
Zfish   684 SIPPPAAVSVE-------------SYSQSAFQCSPMESIQVA-----SLPRVQAQKPTVPMIAET 730

  Fly   976 --PPIDTKPYLREDYRPK------------SPFVSALTTAPDRPFEGHFDKDVPIH--------- 1017
              ||.|....|..|..||            :|..|..|::|..|......::.|..
Zfish   731 IVPPDDMVTSLATDMHPKGIAISSQTSSILTPTASETTSSPVIPLSPVVYREKPASVGGRTGILQ 795

  Fly  1018 ----------MIDLPTPK------EHLSMCDALCTAPERGYTPLNPENAMHRVDEEQKQQELKKR 1066
                      |..:|..|      |.|:|...|...|..||.  .|:|.::.:||.:
Zfish   796 DARRRSAYKPMFKMPDSKKNSPNPELLTMVQNLDDRPSHGYP--EPDNIVYNIDENR-------- 850

  Fly  1067 EFQVLDHEEELGIRPEPPQSVEYYETRRDQPRKSSAFAAMQAFQPSREPLSSNTVSNAGSVADTP 1131
                        .|..||                                          ||..|
Zfish   851 ------------TRVPPP------------------------------------------VAPKP 861

  Fly  1132 RASIVSALKEETDLEYQKYLKAQQRNQKRLDYF-----HQKEEELSGLQGQQLTQL--QRELS-- 1187
            |  ::..:.:....| .|..:...|.|.|:|.|     :.:...|...|.|.:..|  .||||
Zfish   862 R--VIPEMSQIPQAE-GKGAELFARRQSRMDQFVVDTPYLQPATLQHQQSQSVIDLIQPRELSPT 923

  Fly  1188 ----NQQQNLLSQQQLQQSKLLQLQQCVQSQELQQQVQHLTQKS------------------QQQ 1230
                ....|:.:...:..:.||.....|..|....:|...:.|.                  ::|
Zfish   924 PSQWKYSPNVRAPPPIGYNPLLSPSCPVGVQRAGAKVSEGSAKGSKGSYGVPKEGIKALDFMRRQ 988

  Fly  1231 PPQANQQQQQQQQQRGTQQQQHSQVTQRTQQQQQQVPQQVTQQQQQEHSLLSQTTLAETQTLQAN 1295
            |.|.|..........|||....|...|:.:......|:|:..:..:.:.:...:|.........|
Zfish   989 PYQLNPAMFSFGGGIGTQSSIPSYQRQQREGHTLTPPKQIPVKAARVYEIKRFSTPTPMSAPTLN 1053

  Fly  1296 AQSQSSASYSSKATACSNSSSTVPPANTSTAFAPAPAP----APTSIPVRPSAIAVQSSYCSSQF 1356
            .......|.::.....|.|..|.||        |.|.|    ||:..|..|
Zfish  1054 PTVIIPRSQTTLGERISRSDMTSPP--------PEPVPETSLAPSRAPGLP-------------- 1096

  Fly  1357 DVHELIEETAEELEHSEVLFPPPSPLSHLTKQGKAVQSGLHKADSIPKYQRNWTVL---PTQSPI 1418
               ||.:.::..:.| .:.:.||.|:|.::...   .|||..|... |.....:.|   |.:|||
Zfish  1097 ---ELPKISSVPIPH-PMPYSPPVPISSMSNLS---YSGLQAAKQF-KSAPELSALPPNPLKSPI 1153

  Fly  1419 RTPEP 1423
            :.|:|
Zfish  1154 QVPKP 1158

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zasp52	NP_001027420.2	PDZ_ZASP52-like	8..88	CDD:467281	27/69 (39%)
		DUF4749	150..>218	CDD:464948	12/67 (18%)
		LIM_ALP_like	282..333	CDD:188746	0/50 (0%)
		PHA03247	<762..1006	CDD:223021	62/304 (20%)
		LIM1_Enigma_like_1	2020..2073	CDD:188839
		LIM	2081..2132	CDD:259829
		LIM3_Enigma_like_1	2140..2193	CDD:188845
synpo2la	XP_009305650.2	PDZ_SYNPO2-like	8..83	CDD:467264	26/67 (39%)
		PHA03247	<491..961	CDD:223021	105/563 (19%)