Protein Alignment Zasp52 and Ldb3

DIOPT Version :10

• Sequence 1: NP_001027420.2
• Gene: Zasp52 / 36740
• FlyBaseID: FBgn0265991
• Length: 2194
• Species: Drosophila melanogaster
• Sequence 2: XP_006252699.3
• Gene: Ldb3 / 498587
• RGDID: 1564875
• Length: 771
• Species: Rattus norvegicus
• Alignment Length: 717
• Identity: 210/717 - (29%)
• Similarity: 308/717 - (42%)
• Gaps: 121/717 - (16%)

  Fly  1542 THARNYNELNAS-------------PFPDRTRSPAPGPPPNPLNAIRAPRMKEP--ETKSNILSV 1591
            ||....|::.::             |.|..|.:|   |..:||..|  |..|:|  :|.|::.:.
  Rat   106 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAP---PIQSPLPVI--PHQKDPSLDTNSSLATP 165

  Fly  1592 SGGPRLQTGSITTGQSYQGQLLAHS-EQSSQSASQSYNQQPERITEQRVGNLNIQQREQSSQLQQ 1655
            |..|..:....|:|....|...:.| .|:|...|......|       |..|.....:.||:..|
  Rat   166 SPSPEARASPGTSGTLEFGDTFSSSFSQTSVCTSHMEASGP-------VLPLGSPVAKASSEGTQ 223

  Fly  1656 QAQSQT----QSQTR---SQVGNTQIERRRKVTEEFERTQSAKT--IEIRTGSQSVSQSKAQSQS 1711
            .:.|..    .||.|   :.:|....|..|::.:.::.:...|.  ..:..||..|......|.|
  Rat   224 GSVSPKVLPGPSQPRLYNNPIGLYSAETLREMAQMYQMSLRGKASGAGLLGGSLPVKDLAVDSAS 288

  Fly  1712 -ISQAQTQAQSQSQNQSDT-ERRSSYGKTGFVASQAKRLSCMEEEISSLTSQSQAISARASALGE 1774
             :.||..:.||:.::::|. .||||.     :.|::.|:      ::.:|...........||..
  Rat   289 PVYQAVIKTQSKPEDEADEWARRSSN-----LQSRSFRI------LAQMTGTEYMQDPDEEALRR 342

  Fly  1775 GCFPNLRSP--TFDSKFPLKPAPAESIVPGYATVPAATKMLTAPP-----------------PGF 1820
            ...|...:|  |..:..||.||.|.|        |||...:.|.|                 |..
  Rat   343 SSTPIEHAPVCTSQATSPLLPASAPS--------PAAASPIAASPTLATAAAAHAVAASAAGPAS 399

  Fly  1821 LQQQQQQQQRSAFSGYQATTSSVQQSSFASSSKATTSSLSSSSASASASASVARSSQSLTQASAI 1885
            ...:..:.|.||:|...||          |.:.|..:|.|...|:.:....|      :|.||..
  Rat   400 SPVENPRPQASAYSPAAAT----------SPAPAAHTSYSEGPAAPAPKPRV------VTTASIR 448

  Fly  1886 TTTTNNQATTAYRSSNGSITKPN-LASRPSIASITAPGSASAPAPVPSAAPTKATAPFKAPIVPK 1949
            .:.......:.|..|.|:...|. ....|:.|...:|.....|:|.|:.:|:.|.|...:|....
  Rat   449 PSVYQPVPASPYSPSPGANYSPTPYTPSPAPAYTPSPAPTYTPSPAPTYSPSPAPAYTPSPAPNY 513

  Fly  1950 SVIANAVNAAAPPAPAVFPPDLSDLNLNSNVDNSPGAGGKSAGAFGATSAPKRGRGILNKAAGPG 2014
            :...:|..:..|...|..||.::|.:.:...     |.|||..:....:.| ||....| ..||.
  Rat   514 NPTPSAAYSGGPSESASRPPWVTDDSFSQKF-----APGKSTTSVSKQTLP-RGAPAYN-PTGPQ 571

  Fly  2015 V------------------RIPLCNSCNVQIRGPFITALGRIWCPDHFICVNGNCRRPLQDIGFV 2061
            |                  |.|||..||..|||||:.|:||.|.|:.|.|  ..|:..|.|:.||
  Rat   572 VTPLARGTFQRAERFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFNC--AYCKTSLADVCFV 634

  Fly  2062 EEKGDLYCEYCFEKYLAPTCSKCAGKIKGDCLNAIGKHFHPECFTCGQCGKIFGNRPFFLEDGNA 2126
            ||:.::|||.|:|::.||.|:||..||.|:.::|:.:.:|..||.|..|.|.|||..|.:|||..
  Rat   635 EEQNNVYCERCYEQFFAPICAKCNTKIMGEVMHALRQTWHTTCFICAACKKPFGNSLFHMEDGEP 699

  Fly  2127 YCEADWNELFTTKCFACGFPVEAGDRWVEALNHNYHSQCFNCTFCKQNLEGQSFYNKGGRPFCKN 2191
            |||.|:..||:|||..|.|||||||:::|||.|.:|..||.|..|..|||||.||:|..:|.||.
  Rat   700 YCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDKPLCKK 764

  Fly  2192 HA 2193
            ||
  Rat   765 HA 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zasp52	NP_001027420.2	PDZ_ZASP52-like	8..88	CDD:467281
		DUF4749	150..>218	CDD:464948
		LIM_ALP_like	282..333	CDD:188746
		PHA03247	<762..1006	CDD:223021
		LIM1_Enigma_like_1	2020..2073	CDD:188839	25/52 (48%)
		LIM	2081..2132	CDD:259829	23/50 (46%)
		LIM3_Enigma_like_1	2140..2193	CDD:188845	29/52 (56%)
Ldb3	XP_006252699.3	PDZ_PDLIM-like	49..127	CDD:467235	3/20 (15%)
		DUF4749	240..342	CDD:464948	23/112 (21%)
		PHA03247	<426..576	CDD:223021	38/162 (23%)
		LIM1_ZASP_Cypher	595..646	CDD:188838	25/52 (48%)
		LIM2_Enigma_like	654..705	CDD:188748	23/50 (46%)
		LIM3_ZASP_Cypher	713..767	CDD:188844	31/54 (57%)