DRSC/TRiP Functional Genomics Resources

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Protein Alignment Zasp52 and LHX8

DIOPT Version :9

Sequence 1:NP_001027420.2 Gene:Zasp52 / 36740 FlyBaseID:FBgn0265991 Length:2194 Species:Drosophila melanogaster
Sequence 2:XP_016856805.1 Gene:LHX8 / 431707 HGNCID:28838 Length:363 Species:Homo sapiens


Alignment Length:216 Identity:47/216 - (21%)
Similarity:75/216 - (34%) Gaps:69/216 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly  1983 SP-GAGGKSAGAFGATSAPKRGRGILNKAAG--PGVRIPLCNSCNVQIRGPFITALGRIWCPDHF 2044
            || |||.:.:.:..|..:|......:...:|  ||..:  ||||.::|                 
Human    27 SPEGAGDEDSCSSSAPLSPSSSPRSMASGSGCPPGKCV--CNSCGLEI----------------- 72

  Fly  2045 ICVNGNCRRPLQDIGFVEEKGDLYCEYCFEKYLAPTCSKCAGKIKGDCLNAIGKHFHPECFTCGQ 2109
                                        .:|||......|               :|..|.:|..
Human    73 ----------------------------VDKYLLKVNDLC---------------WHVRCLSCSV 94

  Fly  2110 CGKIFG-NRPFFLEDGNAYCEADWNELFTTKCFACGFPVEAGDRWVEALNHN-YHSQCFNCTFCK 2172
            |....| :...:::|.:.:|:.|:...:.|:|..||..:.:.| ||.....| ||..||.|..||
Human    95 CRTSLGRHTSCYIKDKDIFCKLDYFRRYGTRCSRCGRHIHSTD-WVRRAKGNVYHLACFACFSCK 158

  Fly  2173 QNLE-GQSFYNKGGRPFCKNH 2192
            :.|. |:.|.....:..|:.|
Human   159 RQLSTGEEFALVEEKVLCRVH 179

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Zasp52NP_001027420.2 PDZ_signaling 6..87 CDD:238492
DUF4749 150..>217 CDD:292558
LIM_ALP_like 282..333 CDD:188746
LIM1_Enigma_like_1 2020..2073 CDD:188839 5/52 (10%)
LIM 2081..2132 CDD:259829 8/51 (16%)
LIM3_Enigma_like_1 2140..2193 CDD:188845 19/55 (35%)
LHX8XP_016856805.1 None
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R6207
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.940

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