DRSC/TRiP Functional Genomics Resources

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Protein Alignment Zasp52 and pitx3

DIOPT Version :9

Sequence 1:NP_001027420.2 Gene:Zasp52 / 36740 FlyBaseID:FBgn0265991 Length:2194 Species:Drosophila melanogaster
Sequence 2:NP_991238.1 Gene:pitx3 / 402974 ZFINID:ZDB-GENE-041229-4 Length:293 Species:Danio rerio


Alignment Length:329 Identity:74/329 - (22%)
Similarity:117/329 - (35%) Gaps:104/329 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly  1579 MKEPETKSNILSV--SGGPRLQTGSITTGQSYQGQLLAHSEQSSQSASQSYNQQPERITEQRVGN 1641
            :.:.|.:|..||:  ||.|:...|.       :||..:.:|:|.|:.:...|  ||.      |:
Zfish     6 LTDSEARSPALSLSDSGTPQHDPGC-------KGQDNSDTEKSHQNHTDESN--PED------GS 55

  Fly  1642 LNIQQREQ-----SSQLQQ-----QAQSQTQSQTRSQVG----------NTQIERRRKVTEEFER 1686
            |..:||.|     |.|||:     |........||.::.          ....:.||....:.||
Zfish    56 LKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER 120

  Fly  1687 TQSAKTIEIRTGSQ-------------SVSQSKAQSQSISQAQTQAQS----QSQNQSDTERRSS 1734
            .|.|:..:...|:|             ..|.:...::|::.:...|:|    .|.|.|.      
Zfish   121 NQQAELCKNGFGAQFNGLMQPYDDMYSGYSYNNWATKSLASSPLSAKSFPFFNSMNVSP------ 179

  Fly  1735 YGKTGFVASQAKRLSCMEEEISSLTSQSQAISARASAL----GEGC-----FPNLRSPTFDSKFP 1790
                  ::||.     |....||:.|.:.|.|...||:    |.|.     ..||.|||.:|   
Zfish   180 ------LSSQP-----MFSPPSSIPSMNMASSMVPSAVAGVPGSGLNNLGNLNNLNSPTLNS--- 230

  Fly  1791 LKPAPAESIVPGYATVPAATKMLTAPPPGF----------LQQQQQQQQRSAFSGYQATTSSVQQ 1845
               |...:....|||        ||.|..:          |:.:.:|....|:...|...|::..
Zfish   231 ---AAVSAAACPYAT--------TAGPYMYRDTCNSSLASLRLKAKQHANFAYPAVQNPVSNLSP 284

  Fly  1846 SSFA 1849
            ..:|
Zfish   285 CQYA 288

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Zasp52NP_001027420.2 PDZ_signaling 6..87 CDD:238492
DUF4749 150..>217 CDD:292558
LIM_ALP_like 282..333 CDD:188746
LIM1_Enigma_like_1 2020..2073 CDD:188839
LIM 2081..2132 CDD:259829
LIM3_Enigma_like_1 2140..2193 CDD:188845
pitx3NP_991238.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..69 21/77 (27%)
Cnd2 18..>79 CDD:303063 21/75 (28%)
Homeobox 64..116 CDD:278475 9/51 (18%)
OAR 251..268 CDD:281777 2/16 (13%)
OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138 255..268 2/12 (17%)
Nuclear localization signal. /evidence=ECO:0000250|UniProtKB:O35160 260..264 1/3 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R6207
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.030

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