Protein Alignment Zasp52 and ldb3

DIOPT Version :10

• Sequence 1: NP_001027420.2
• Gene: Zasp52 / 36740
• FlyBaseID: FBgn0265991
• Length: 2194
• Species: Drosophila melanogaster
• Sequence 2: XP_017950805.1
• Gene: ldb3 / 394699
• XenbaseID: XB-GENE-922381
• Length: 818
• Species: Xenopus tropicalis
• Alignment Length: 938
• Identity: 231/938 - (24%)
• Similarity: 355/938 - (37%)
• Gaps: 267/938 - (28%)

  Fly  1376 FPPPSPLSHLTKQGKAVQSGLHKADSIPKYQRNWTVLPTQSPIRTPEPQELRENVPLAFVDAPKA 1440
            |..|..:|.:|...||.||.:::.|.:                              ..:|.
 Frog    23 FNMPLTISRVTPGSKAAQSSVNQGDLV------------------------------VAIDG--- 54

  Fly  1441 PVTSDSSTVHRPIAQVAAPTTVVAPSREREKERRPQLSVPIIVEDRSGPVTMAFQPLDELVRPDQ 1505
             |.:|..| |             ..::.:.|.....|.:.:....|.|||..|
 Frog    55 -VNTDGMT-H-------------LEAQNKIKSASYNLGLTLQKSKRPGPVPTA------------ 92

  Fly  1506 ALTPTRPYTPSLTNKPAPIVPFYQTEEKLVFEECSATHARNYNELNASPFPDRT-------RSPA 1563
                    ||.: :.|.|::| :|.:..|              |:|.|    ||       :|..
 Frog    93 --------TPRM-DSPMPVIP-HQKDHAL--------------EINGS----RTAYSTVSSKSAV 129

  Fly  1564 PGPPPNPLNAIRAPRMKEPET----KSNILSVSGGPRLQTGSITTGQS-YQGQLLAHSEQSSQSA 1623
            |.......|...|..:.:.||    .|..:..|....:.|.|:.:..| .:|.:.:..:.....|
 Frog   130 PLVGSMSTNETMAGYVSKQETNHSHSSTFIKTSVRTSMSTHSVASDASPIKGSIGSKVDPLVSGA 194

  Fly  1624 SQSYNQ---QPERITEQRVGNLNIQQREQSSQLQQQAQSQTQSQTRSQVGNTQ-----IERRRKV 1680
            :...||   ...|:....||..:.:...:.:::.:.:.....|:.....||..     ::....|
 Frog   195 NNPINQFSPSKNRLYNNPVGLYSAETLNEMAEMHKLSLKGRASEGGLHRGNLPVKDPLVDIASPV 259

  Fly  1681 TEEFERTQSAKTIEIRTGSQSVSQSKAQSQSISQAQTQAQSQSQNQSDTERRSSYGKTGFVASQA 1745
            .:...:.|.....||...::..:..:::|..:....|..:.......|..||:|
 Frog   260 YQAVLKNQGKTESEIDDWARRAANLQSKSFRVLAHITGTEYMQDPDEDALRRAS----------- 313

  Fly  1746 KRLSCMEEEISSLTSQSQAISARASALGEGCFPNLRSPTFD-------SKFPLKPAPAESIVPGY 1803
                         :.::.|.|...|..|....|:.||.|:.       ...|.:|:|..|  .||
 Frog   314 -------------SKENVAKSPEISPAGAKVLPSARSGTWHPTKSPTREDIPSQPSPVSS--RGY 363

  Fly  1804 A------TVPAAT-------KMLTAPPPGFLQQQQQQQQRSAFSGYQATTSSVQQSSFASSSKAT 1855
            :      :||...       .:....||                    .||:.:::..|:|..|:
 Frog   364 SVRFGGDSVPRKNVHTSTDQNLPKLSPP--------------------ITSTYKRAPAAASISAS 408

  Fly  1856 TSSLSSS---SASASASASVARSSQSLTQASAITTTTNNQATTAYRSSN--------GSITKPNL 1909
            ..:...|   |.:||..:|...:..|..|.|:.|||..::|:.::.||.        |:.::|..
 Frog   409 QKTFQGSKNMSIAASTISSAISAQSSHQQQSSFTTTYQSKASQSFSSSTTAKGPVPYGAYSEPAA 473

  Fly  1910 A--------SRPSIASITAPGSASAPA---PVP---------SAAP----------TKAT----- 1939
            .        |.|:.......|..|.||   |||         |:||          |.|:
 Frog   474 KGPVPYGGYSEPAAKGPVPYGGYSEPAAKGPVPYGGYSEPAASSAPAAPAPKPRVVTTASIKPSV 538

  Fly  1940 -----APFKAPIVPKSVIANAVNAAAPPA--PAVFPPDLSDLNLNSNVDNSPGAGGKSAGAFGAT 1997
                 ||...|:.|.:.|      .|||.  |:..||.::|.|.:...     |.|||.......
 Frog   539 YQPSQAPAPGPVQPPAQI------YAPPTQEPSNRPPWVTDDNFSQKF-----APGKSTSTVTKQ 592

  Fly  1998 SAPKRG-------------------------RGILNKAA--GPGVRIPLCNSCNVQIRGPFITAL 2035
            ..||..                         ||::.:|.  ....|.|||.|||..|||||:.|:
 Frog   593 ILPKAAPLPPTPISAPSYTPQPVGQSPSQVPRGLIQRAERFPASSRTPLCASCNSIIRGPFLVAM 657

  Fly  2036 GRIWCPDHFICVNGNCRRPLQDIGFVEEKGDLYCEYCFEKYLAPTCSKCAGKIKGDCLNAIGKHF 2100
            ||.|.|:.|.|  .:|:..|.|:.||||:..:|||.|:|::.||||::|..||.|:.::|:.:.:
 Frog   658 GRSWHPEEFNC--AHCKTSLADVSFVEEQKGVYCERCYEQFFAPTCARCNTKIMGEVMHALRQTW 720

  Fly  2101 HPECFTCGQCGKIFGNRPFFLEDGNAYCEADWNELFTTKCFACGFPVEAGDRWVEALNHNYHSQC 2165
            |..||.|..|.|.|||..|.:|||..|||.|:..||:|||..|.|||||||:::|||.|.:|..|
 Frog   721 HTTCFVCAACRKPFGNSLFHMEDGEPYCEKDYVALFSTKCHGCDFPVEAGDKFIEALGHTWHDTC 785

  Fly  2166 FNCTFCKQNLEGQSFYNKGGRPFCKNHA 2193
            |.|..|..|||||.||:|..:|.||.||
 Frog   786 FICAVCHVNLEGQPFYSKKDKPLCKKHA 813

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zasp52	NP_001027420.2	PDZ_ZASP52-like	8..88	CDD:467281
		DUF4749	150..>218	CDD:464948
		LIM_ALP_like	282..333	CDD:188746
		PHA03247	<762..1006	CDD:223021
		LIM1_Enigma_like_1	2020..2073	CDD:188839	26/52 (50%)
		LIM	2081..2132	CDD:259829	22/50 (44%)
		LIM3_Enigma_like_1	2140..2193	CDD:188845	29/52 (56%)
ldb3	XP_017950805.1	PDZ_PDLIM-like	4..82	CDD:467235	16/106 (15%)
		DUF4749	209..311	CDD:464948	12/101 (12%)
		MISS	<462..625	CDD:318115	35/173 (20%)
		LIM1_ZASP_Cypher	642..693	CDD:188838	26/52 (50%)
		LIM2_Enigma_like	701..752	CDD:188748	22/50 (44%)
		LIM3_Enigma_like	760..813	CDD:188749	29/52 (56%)