DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp52 and Lpxn

DIOPT Version :9

Sequence 1:	NP_001027420.2	Gene:	Zasp52 / 36740	FlyBaseID:	FBgn0265991	Length:	2194	Species:	Drosophila melanogaster
Sequence 2:	XP_038964643.1	Gene:	Lpxn / 293783	RGDID:	1304981	Length:	398	Species:	Rattus norvegicus

Alignment Length:	307	Identity:	88/307 - (28%)
Similarity:	127/307 - (41%)	Gaps:	55/307 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly  1921 PGSASAPAPVPSAAPTKA-TAPFKAPIVPKSVI--ANAVNAAAPPAPAVFPP------DLSDL-- 1974
            |...|.....|....|:. |:|.|..:|..:.|  .|..:....|..:|.||      .|.:|
  Rat    46 PTQESKLPQTPKTLSTQGNTSPLKVQLVYTTNIQEPNVYSEVQEPKQSVLPPKTSAAAQLDELMA 110

  Fly  1975 NLN------------------------SNVDNSPGAGGKSAGAFGATSAPKRGRGILNKAAGPGV 2015
            :||                        :::|:..|...:.....|..:.|| |.
  Rat   111 HLNELQAKVSVKADASRKPLPDKQDHKASLDSMLGGLEQELQDLGIATVPK-GH----------- 163

  Fly  2016 RIPLCNSCNVQIRGPFITALGRIWCPDHFICVNGNCRRPLQDIGFVEEKGDLYCEYCFEKYLAPT 2080
                |.||...|.|..|.|||:.|.|:||:|.  :|:..|....|.|..|..||...:....:|.
  Rat   164 ----CASCQKPIAGKVIHALGQSWHPEHFVCT--HCKEELGSSPFFERNGLAYCSKDYHHLFSPR 222

  Fly  2081 CSKCAGKIKGDCLNAIGKHFHPECFTCGQCGKIFGNRPFFLEDGNAYCEADWNELFTTKCFACGF 2145
            |:.||..|....|.|:.|.:|||.|.|..||::||...|..:|...||..|:..:|:.||..|..
  Rat   223 CAYCAAPITDKVLTAMNKTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNR 287

  Fly  2146 PVEAGDRWVEALNHNYHSQCFNCTFCKQNLEGQSFYNKGGRPFCKNH 2192
            ||.  :.::.|:|..:|.:||.|..|..:....||:...|||||:.|
  Rat   288 PVL--ENYLSAMNTVWHPECFVCGDCFSSFSSGSFFELDGRPFCELH 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp52	NP_001027420.2	PDZ_signaling	6..87	CDD:238492
		DUF4749	150..>217	CDD:292558
		LIM_ALP_like	282..333	CDD:188746
		LIM1_Enigma_like_1	2020..2073	CDD:188839	21/52 (40%)
		LIM	2081..2132	CDD:259829	20/50 (40%)
		LIM3_Enigma_like_1	2140..2193	CDD:188845	19/53 (36%)
Lpxn	XP_038964643.1	LIM1_Leupaxin	162..216	CDD:188790	22/70 (31%)
		LIM	223..274	CDD:413332	20/50 (40%)
		LIM	282..334	CDD:413332	19/53 (36%)
		LIM4_Paxillin_like	341..392	CDD:188725
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1703
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810