DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp52 and rga1

DIOPT Version :9

Sequence 1:	NP_001027420.2	Gene:	Zasp52 / 36740	FlyBaseID:	FBgn0265991	Length:	2194	Species:	Drosophila melanogaster
Sequence 2:	NP_596743.1	Gene:	rga1 / 2541022	PomBaseID:	SPBC3F6.05	Length:	1150	Species:	Schizosaccharomyces pombe

Alignment Length:	266	Identity:	66/266 - (24%)
Similarity:	104/266 - (39%)	Gaps:	59/266 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly  1961 PPAPAVFPPDLSDLNLNSNVDNSPGAGGKS--AGAFGATSAPKR-----------------GRGI 2006
            ||.....|...:.:..||...|.|.:...|  ||..|.:|..:|                 ..|:
pombe    22 PPKRIPVPSRQNKIEENSTTKNFPHSRHTSTVAGTEGGSSLSRRHTSAESRKALPNQQQLAQSGL 86

  Fly  2007 LNKAAGPGVR------IP----------LCNSCNVQIRGPFITALGRIWCPDHFICVNGNCRR-- 2053
            |||.....::      .|          :|.||...|.|.::.|||.|:..:.|.|  .:|..
pombe    87 LNKEEQQSLKRSDTSVFPKAVRKVSSSKICASCGQVISGQYVRALGNIYHLECFRC--HDCNSLV 149

  Fly  2054 -----PLQDIGFVEEKGDLYCEYCFEKYLAPTCSKCAGKIKGDCLNAIGKHFHPECFTCGQCGKI 2113
                 |:.|...  .|....||..:.:.|...|:.|...::|..:.|:.|.||.|.|||..|..:
pombe   150 ASKFFPIDDPTL--NKQVPLCETDYFRRLDLLCASCGMALRGYYITALNKKFHIEHFTCSLCYTV 212

  Fly  2114 FG-NRPFFLEDGNAYCEADWNELFTTKCFACGFPVEAGDRWVE----ALNHNYHSQC------FN 2167
            || |..::..:|..||...::.||..:|..|..|:..  ::||    .::.|:|..|      :|
pombe   213 FGPNDSYYEYEGKVYCHYHYSTLFAARCCGCDGPILR--QFVEVYRNGVSQNWHVPCHMIYKFWN 275

  Fly  2168 CTFCKQ 2173
            ...|::
pombe   276 VKLCQK 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp52	NP_001027420.2	PDZ_signaling	6..87	CDD:238492
		DUF4749	150..>217	CDD:292558
		LIM_ALP_like	282..333	CDD:188746
		LIM1_Enigma_like_1	2020..2073	CDD:188839	17/59 (29%)
		LIM	2081..2132	CDD:259829	18/51 (35%)
		LIM3_Enigma_like_1	2140..2193	CDD:188845	10/44 (23%)
rga1	NP_596743.1	LIM1_Lrg1p_like	116..172	CDD:188777	17/59 (29%)
		LIM2_Lrg1p_like	180..232	CDD:188778	18/51 (35%)
		LIM	485..539	CDD:295319
		RhoGAP_fLRG1	835..1044	CDD:239862
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1703
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	1	1.000	-	-		otm47179
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.900