DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp52 and F33D11.1

DIOPT Version :9

Sequence 1:	NP_001027420.2	Gene:	Zasp52 / 36740	FlyBaseID:	FBgn0265991	Length:	2194	Species:	Drosophila melanogaster
Sequence 2:	NP_491698.1	Gene:	F33D11.1 / 185224	WormBaseID:	WBGene00018000	Length:	131	Species:	Caenorhabditis elegans

Alignment Length:	150	Identity:	40/150 - (26%)
Similarity:	56/150 - (37%)	Gaps:	40/150 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly  2020 CNSCNVQI-RGPFITALGRIWCPDHFICVNGNCRRPLQDIG--FVEEKGDLYCEYCFEKYLAPTC 2081
            |..|:|:: ....|...|::|..:|.:|...|||  :.| |  .|.:.|.:.|..|..|...|.|
Worm     4 CGHCSVKVGEESAILTNGKVWHVNHLLCDLCNCR--IND-GERCVPQNGVILCSECHIKTTRPIC 65

  Fly  2082 SKCAGKIKGDCLNAIGKHFHPECFTCGQCGKIFGNRPFFLEDGNAYCEADWNELFTTKCFACGFP 2146
            ..|...||.:...|:...:||.||.|..|.|     |.         |.|:::|....|
Worm    66 KGCGEFIKTNLCEALNSTWHPTCFQCSVCQK-----PL---------EVDFHQLPNRMC------ 110

  Fly  2147 VEAGDRWVEALNHNYHSQCF 2166
                          .||.||
Worm   111 --------------VHSDCF 116

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp52	NP_001027420.2	PDZ_signaling	6..87	CDD:238492
		DUF4749	150..>217	CDD:292558
		LIM_ALP_like	282..333	CDD:188746
		LIM1_Enigma_like_1	2020..2073	CDD:188839	16/55 (29%)
		LIM	2081..2132	CDD:259829	14/50 (28%)
		LIM3_Enigma_like_1	2140..2193	CDD:188845	4/26 (15%)
F33D11.1	NP_491698.1	LIM	4..57	CDD:295319	16/55 (29%)
F33D11.1	NP_491698.1	LIM	65..>97	CDD:295319	12/36 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1703
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810