Protein Alignment Zasp52 and Pax6

DIOPT Version :9

• Sequence 1: NP_001027420.2
• Gene: Zasp52 / 36740
• FlyBaseID: FBgn0265991
• Length: 2194
• Species: Drosophila melanogaster
• Sequence 2: NP_001231127.1
• Gene: Pax6 / 18508
• MGIID: 97490
• Length: 436
• Species: Mus musculus
• Alignment Length: 524
• Identity: 97/524 - (18%)
• Similarity: 164/524 - (31%)
• Gaps: 160/524 - (30%)

  Fly  1550 LNASPFPDRTRSPA-----PGPPPNPLNAI------RAPRMKEPETKSN-ILSVSGGPRLQTGSI 1602
            :|..|.||.||...     .|..|..::.|      ...::.:.|..|| .:|...|...:||||
Mouse    16 VNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNENVSNGCVSKILGRYYETGSI 80

  Fly  1603 ---TTGQSYQGQLLAHSEQSSQSASQSYNQQPERITEQRVGNLNIQQREQSSQLQQQAQSQTQSQ 1664
               ..|.|                      :|...|.:.|..:...:||..|....:.:.:..|:
Mouse    81 RPRAIGGS----------------------KPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSE 123

  Fly  1665 ---TRSQVGNTQIERR--RKVTEEFERT------QSAKTIEIRTGSQSVSQSKAQSQSISQAQTQ 1718
               |...:.:.....|  |.:..|.::.      ...:.:..:|||...........|:....||
Mouse   124 GVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQ 188

  Fly  1719 --AQSQSQNQSDTERRSSYGKTGFVAS---------QAKRLSCMEEEISSLTSQSQA-----ISA 1767
              .|.|.....:|...||.|:....|.         |..|.|..:|:|.:|..:.:.     :.|
Mouse   189 DGCQQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFA 253

  Fly  1768 RASALGEGCFPNLRSPTFDSKFPLKPAPAESIVPGYATVPAATKMLTAPPPGFLQQQQQQQQRSA 1832
            |.....:...|..|...:.|....|....|.:                        :.|::|.|.
Mouse   254 RERLAAKIDLPEARIQVWFSNRRAKWRREEKL------------------------RNQRRQASN 294

  Fly  1833 FSGYQATTSSVQQSSFASSSKATT--SSLSSSSASASASASVARSSQSLTQASAITTTTNNQATT 1895
            ...:...:||...|.:....:.||  ||.:|.|.......::..:..:|....:.|...
Mouse   295 TPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYSALPPMPSFTMAN------ 353

  Fly  1896 AYRSSNGSITKPNLASRPSIASITAPGSASAPAPVPSAAPTKATAPFKAPIVPKSVIANAVNAAA 1960
                        ||..:|.:.|.|:..|...|           |:|        ||...:.:...
Mouse   354 ------------NLPMQPPVPSQTSSYSCMLP-----------TSP--------SVNGRSYDTYT 387

  Fly  1961 PPAPAVFPPDLSDLNLNSNVDNSPGAGGKSAGAFGATSAPKRGRGILNKAAGPGVRIPLCNSCNV 2025
            ||            ::.:::::.|      .|..|.||.     |:::    |||.:|      |
Mouse   388 PP------------HMQTHMNSQP------MGTSGTTST-----GLIS----PGVSVP------V 419

  Fly  2026 QIRG 2029
            |:.|
Mouse   420 QVPG 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zasp52	NP_001027420.2	PDZ_signaling	6..87	CDD:238492
		DUF4749	150..>217	CDD:292558
		LIM_ALP_like	282..333	CDD:188746
		LIM1_Enigma_like_1	2020..2073	CDD:188839	3/10 (30%)
		LIM	2081..2132	CDD:259829
		LIM3_Enigma_like_1	2140..2193	CDD:188845
Pax6	NP_001231127.1	PAX	4..142	CDD:128645	29/147 (20%)
		Homeobox	228..281	CDD:395001	11/52 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030