DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zasp52 and vab-3

DIOPT Version :9

Sequence 1:	NP_001027420.2	Gene:	Zasp52 / 36740	FlyBaseID:	FBgn0265991	Length:	2194	Species:	Drosophila melanogaster
Sequence 2:	NP_001024570.1	Gene:	vab-3 / 181251	WormBaseID:	WBGene00006870	Length:	455	Species:	Caenorhabditis elegans

Alignment Length:	226	Identity:	46/226 - (20%)
Similarity:	68/226 - (30%)	Gaps:	67/226 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   354 KPNTKLSASTISSALNSHGYGGHSNGYSNGNSTPAPAPVASSQATATVATVAPSAATAATAAATP 418
            |...|.|:.|:.|:|            |||..||.|..|..|..|      .|..:.|:|....|
Worm   277 KMRNKRSSGTMDSSL------------SNGTPTPTPGSVTGSNMT------NPIGSPASTPNRFP 323

  Fly   419 QAATATDSPAATASSSDNMSAYVADEPSSIYGQISAESVALAPPPP----QPPTAGGGDQPFEYV 479
            ...:|..........:..|.|.::......|....|...::||.|.    ||.....|..|:::
Worm   324 SNNSANLPTTNFVPQTSQMYAGLSQPAMDPYSFGIANGFSMAPYPQVTDFQPHHMFQGRSPYDF- 387

  Fly   480 TLTGNVIRSVQAPGKGACPSYKVNQGYARPFGAAAPKSPVSYPPQQQQQSPRPAPGGQNPY---- 540
                                         |:    |:.|.:....||..||.....|..|.
Worm   388 -----------------------------PY----PRMPTNGHGFQQSMSPATTAVGDIPTLSSG 419

  Fly   541 ATLPRSNVGQQGGEAVEELQPEFEEEDCYEM 571
            .:||.|.|       :..:.|.......:|:
Worm   420 MSLPVSAV-------LNSIDPSLTHSQMHEL 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp52	NP_001027420.2	PDZ_signaling	6..87	CDD:238492
		DUF4749	150..>217	CDD:292558
		LIM_ALP_like	282..333	CDD:188746
		LIM1_Enigma_like_1	2020..2073	CDD:188839
		LIM	2081..2132	CDD:259829
		LIM3_Enigma_like_1	2140..2193	CDD:188845
vab-3	NP_001024570.1	PAX	5..129	CDD:128645
		COG5576	183..293	CDD:227863	6/27 (22%)
		Homeobox	221..274	CDD:395001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030