DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Zasp52 and hoxb8

DIOPT Version :9

Sequence 1:	NP_001027420.2	Gene:	Zasp52 / 36740	FlyBaseID:	FBgn0265991	Length:	2194	Species:	Drosophila melanogaster
Sequence 2:	XP_002938067.1	Gene:	hoxb8 / 100493882	XenbaseID:	XB-GENE-990961	Length:	243	Species:	Xenopus tropicalis

Alignment Length:	208	Identity:	42/208 - (20%)
Similarity:	79/208 - (37%)	Gaps:	63/208 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly  1591 VSGGPRLQTGSITTGQSYQ--GQLLAHSEQSSQSASQSYNQQPERIT-------------EQRVG 1640
            :.|.|.:..|: :.|.::|  ||:......:...:|.:|.|.|..:|             .||..
Frog    32 LGGRPTVVYGA-SAGGTFQHPGQIQDFYHGTPSLSSPTYQQNPCAVTCHGDPGSFYGYDPLQRQS 95

  Fly  1641 NLNIQQRE---------QSSQLQQQAQSQTQSQTRSQV----------GNTQIERRRKVTEEFER 1686
            ..:.|..|         .|:.|.::|:|..||.:.:|:          |      ||:..:.:.|
Frog    96 LFSSQDTELVQYSECKLASAGLGEEAESSEQSPSPTQLFPWMRPQAAAG------RRRGRQTYSR 154

  Fly  1687 TQSAKTIEIR---------TGSQSVSQSKAQSQSISQAQTQAQSQSQNQSDTERRSSYGKTGFVA 1742
            .|   |:|:.         |..:.:..|.|    :...:.|.:...||:....::.: .|..|.:
Frog   155 YQ---TLELEKEFLFNPYLTRKRRIEVSHA----LGLTERQVKIWFQNRRMKWKKEN-NKDKFPS 211

  Fly  1743 SQAKRLSCMEEEI 1755
            |:     |.:||:
Frog   212 SK-----CEQEEL 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zasp52	NP_001027420.2	PDZ_signaling	6..87	CDD:238492
		DUF4749	150..>217	CDD:292558
		LIM_ALP_like	282..333	CDD:188746
		LIM1_Enigma_like_1	2020..2073	CDD:188839
		LIM	2081..2132	CDD:259829
		LIM3_Enigma_like_1	2140..2193	CDD:188845
hoxb8	XP_002938067.1	Homeobox	149..202	CDD:365835	10/59 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030