DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Impbeta11 and TRN1

DIOPT Version :9

Sequence 1:	NP_788357.1	Gene:	Impbeta11 / 36732	FlyBaseID:	FBgn0284254	Length:	1075	Species:	Drosophila melanogaster
Sequence 2:	NP_179287.3	Gene:	TRN1 / 816198	AraportID:	AT2G16950	Length:	895	Species:	Arabidopsis thaliana

Alignment Length:	956	Identity:	192/956 - (20%)
Similarity:	330/956 - (34%)	Gaps:	241/956 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 VAQTLQAATNPSHEIVQKAE--AQLREWEQQPGFFPTIARLSMRRGGGGDVVSSTEDSEVKVRWM 86
            :...|:...:|| .:|.|::  .||:.:.|.|.|...:..:.:|          .|...|:||..
plant    18 ICSLLEQQISPS-SVVDKSQIWKQLQHFSQFPDFNNYLVFILVR----------AEGKSVEVRQA 71

  Fly    87 AAVYLKNGVERYWRPNSRQELPAEQKQQIREVLLRHYDAEEVPQVALQVAVLLGRLARTDYPRFW 151
            |.:.|||.:...: |:..|    |.::.|:..||....|.: ..:...|..::..:...:....|
plant    72 AGLLLKNNLRGAY-PSMTQ----ENQKYIKSELLPCLGAAD-RNIRTTVGTIISVIVNIEGVSGW 130

  Fly   152 PDLLPTLMKQLQS-------CGTDGDSALQQRILIVLHYVLKALASRRLMAEQRAFQELGLQIFG 209
            .:|||.|:..|.|       ...|..|.:.:.|..||...:..||.|.:
plant   131 HELLPALVTCLDSNDLNHMDGAMDALSKICEDIPHVLDTEVPGLAERPI---------------- 179

  Fly   210 YLAWDIWAPLTTRFLQ----LVRKDEAMALNALQRAYVVMRTLRKLVVYGCAKPYKSTDHMNFVE 270
                :|:.|...:|.|    .:||   :||.::.:..::|    ..|::...  |.|.|  .:::
plant   180 ----NIFLPRLLQFFQSPHASLRK---LALGSVNQYIIIM----PAVIWQAL--YNSLD--KYLQ 229

  Fly   271 QLFQRLRQCLELRYELKVGSATPGTATILTELE---RFVIKMMKTLNELMERHSVSFARFVPVAL 332
            .||......:....:|...:....|..:.:.:|   |.|::.|..:|...: ..||..     |.
plant   230 GLFVLANDPVPEVRKLVCAAFVHLTEVLPSSIEPHLRNVMEYMLQVNRDPD-EEVSLE-----AC 288

  Fly   333 EFSFHYVFHEGTALIFDAG-DRINFKNFAIQALNMLKGIMLSGNDSISAPPEGGAHIEDELLASA 396
            ||...|.         ||. ...|.|.|..:.:.:|...|...:|             ||.|..|
plant   289 EFWSAYC---------DAQLPPENLKEFLPRLIPVLLENMAYADD-------------DESLLDA 331

  Fly   397 AQSQA----------KFFTAERVTYICEKIVTHYFLLTQQELEEWQQDPEGYDQDDGGGDAWKYA 451
            .:.::          :|.|:.              |...::.:         |.||...:.|.
plant   332 EEDESQPDRDQDLKPRFHTSR--------------LHGSEDFD---------DDDDDSFNVWN-- 371

  Fly   452 LR----PSVETLYFTCFTQHSQVMIPEVLRFVRRAQQLQLTPESDLKAILLKDAIYNAVGQAAFH 512
            ||    .:::.|        |.|...|:|..:....|..|:...| :|...::|...|:|..|..
plant   372 LRKCSAAAIDVL--------SNVFGDEILPALMPLIQKNLSASGD-EAWKQREAAVLALGAIAEG 427

  Fly   513 FFNKL-----DFGAWLTSQLLAELRVEALNFRILRRRIIWLVGHWVGVQLPRELRPLAYE----A 568
            ..|.|     :..|:|. .||.:      .|.::|....|.:..:....:.....|..||    .
plant   428 CMNGLYPHLSEIVAFLL-PLLDD------KFPLIRSISCWTLSRFGKYLIQESGNPKGYEQFEKV 485

  Fly   569 CLHLLRPQEDMPTRL--AAARTLNLLIDDFEFMPEAFHPYFPSLFEALFLLLHEAGECDTKIV-- 629
            .:.|||...|...|:  ||......:.:|   ..|...|:...:.:.|.....:....:.:||
plant   486 LMGLLRRLLDTNKRVQEAACSAFATVEED---AAEELVPHLGVILQHLMCAFGKYQRRNLRIVYD 547

  Fly   630 VLGTMTLLVEKMSEYIEPQALQFIAYLPLL--WRESEEHD-----LLRCAIIGTLEQLVRTIRDV 687
            .:||   |.:.:.|.:...|...|...||:  |::....|     ||.|  ..::.|.:..
plant   548 AIGT---LADSVREELNKPAYLEILMPPLVAKWQQLSNSDKDLFPLLEC--FTSISQALGV---- 603

  Fly   688 PEPMKPFLYSVIELSTD---LQQPSHVYLIEDGIMLWLAVIGNSTALTPELLGLCDHLLPIIE-- 747
              ...||...|.:...|   |||.:.|.....|.......|..|..|   |.||.:.|...||
plant   604 --GFAPFAQPVFQRCMDIIQLQQLAKVNPASAGAQYDREFIVCSLDL---LSGLAEGLGSGIESL 663

  Fly   748 MSSENLRTVLQLIHAYILLDAQAYLSRYGEGFVAYCVRSFEDIR-----VEGIIAML-------R 800
            :...|||.:|                      :..|:....|:|     :.|.:|.:       |
plant   664 VQQSNLRDLL----------------------LNCCIDEAADVRQSAFALMGDLARVFPVYLQPR 706

  Fly   801 IIETCLKTDAALGLRLVRPALPFVFQQVC---------LKQEYPMTMGWYLTIVARTLLIDQSVF 856
            :::........|...|.|..|. |....|         ::||....:...::.:...|...:.|.
plant   707 LLDFLEIASQQLSANLNRENLS-VANNACWAIGELAVKVRQEVSPIVAKVVSSLGLILQHGEGVN 770

  Fly   857 MSVVQQLPQADALARILDVWIEMFPMVPDTHAEK-RKLFCLAFASI 901
            .::|:.  .|..|.|:  .||.  |.:...|.:. .|.:|:|.:.:
plant   771 KALVEN--SAITLGRL--AWIR--PDLVAPHMDHFMKPWCMALSMV 810

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Impbeta11	NP_788357.1	CSE1	23..>768	CDD:227944	165/799 (21%)
Impbeta11	NP_788357.1	IBN_N	42..120	CDD:197981	18/79 (23%)
TRN1	NP_179287.3	IBN_N	38..104	CDD:281761	20/80 (25%)
		HEAT repeat	99..120	CDD:293787	4/21 (19%)
		HEAT repeat	133..161	CDD:293787	8/27 (30%)
		HEAT repeat	181..211	CDD:293787	8/32 (25%)
		HEAT repeat	226..252	CDD:293787	3/25 (12%)
		HEAT repeat	265..293	CDD:293787	9/33 (27%)
		HEAT_2	392..507	CDD:290374	28/122 (23%)
		HEAT repeat	395..426	CDD:293787	7/31 (23%)
		HEAT_EZ	411..465	CDD:290247	13/60 (22%)
		HEAT repeat	438..468	CDD:293787	7/36 (19%)
		HEAT repeat	484..510	CDD:293787	7/25 (28%)
		HEAT repeat	527..552	CDD:293787	5/27 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000