Protein Alignment Impbeta11 and xpo-2

DIOPT Version :9

• Sequence 1: NP_788357.1
• Gene: Impbeta11 / 36732
• FlyBaseID: FBgn0284254
• Length: 1075
• Species: Drosophila melanogaster
• Sequence 2: NP_490716.1
• Gene: xpo-2 / 171621
• WormBaseID: WBGene00002079
• Length: 938
• Species: Caenorhabditis elegans
• Alignment Length: 1060
• Identity: 212/1060 - (20%)
• Similarity: 378/1060 - (35%)
• Gaps: 315/1060 - (29%)

  Fly    20 VEQLVAQTLQAATNPSHEIVQKAEAQLREWEQQPGFFPTIARLSMRRGGGGDVVSSTEDSEVKVR 84
            :||:.| .||....|...|.::.|..||..:..||:...|.:|         ||:..:....::|
 Worm     1 MEQIGA-ALQQTLEPDAAIRKRGEEALRSLQSNPGYIIQILQL---------VVNEQQQIAPQIR 55

  Fly    85 WMAAVYLKNGVERYWRPNSRQELPAEQKQQIREVLLR-HYDAEEVPQVALQVAVLLGRLARTDYP 148
            ..|||.|||.|:|.|.|....|:..|.::|.|.:||. .::.:...|..|..|:.|  :|:.|:|
 Worm    56 IAAAVALKNFVKRNWGPAPEVEMGQEDEEQFRSMLLEAMFNTKSNVQEILSNALYL--IAQRDFP 118

  Fly   149 RFWPDLLPTLMKQLQSCGTDGDSALQQRILIVLHYVLKALASRRLMAEQRAFQELGLQIFGYLAW 213
            ..||||:|.|.|.|.  |.|            |::::.:|||...:..:..|:....:::..|..
 Worm   119 EKWPDLVPYLSKFLN--GAD------------LNHLVASLASMEQIFRKFRFESKSAELWKELKK 169

  Fly   214 DIWA---PLTTRFLQLV----RKDEAMALNALQRAYVVMRTLRKLVVYGCAKPYKSTDHMNFVEQ 271
            .:.:   |||.....::    |||:   |.|.:    :.:.||.|::  .||.|.|.......|.
 Worm   170 CLLSTQEPLTLLLRNMMEVGQRKDQ---LGADE----IAQWLRVLLL--IAKVYHSLCSQEIPEY 225

  Fly   272 LFQRLRQCLE-----LRYELKVGSATPGTATILTELERFVIKMMKTLNELMERHSVSFARFVPVA 331
            ....|:..:.     ::.:....::..|..|.|.||:..:.::....:   :|:....:.|||..
 Worm   226 FEDHLKDWMPHFLHLVQIDAPTQTSNSGEPTTLDELKHEICEIFTLYS---QRYEEEISEFVPDI 287

  Fly   332 LEFSFHYVFHEGTALIFDAGDRINFKNFAIQALNMLKGIMLSGNDSISAPPEGGAHIEDELLASA 396
            :...::        |:...|....:......||..|.                        :.|.
 Worm   288 ILAVWN--------LLKSTGPDTRYDTMVCAALEFLS------------------------MVSQ 320

  Fly   397 AQSQAKFFTAERV-TYICEKIVTHYFLLTQQELEEWQQDPEGYDQDD------------------ 442
            .|.....||.|.| ..:.|.:.....||.||::|.::.:|..|.:.|
 Worm   321 RQYYEGHFTGEGVLKTLAENVCVQNLLLRQQDMELFEDEPLDYMKRDIEGTDVGTRRRGAIDLAR 385

  Fly   443 ----------------------GGGDAWK----YAL------------------RPSVE--TLYF 461
                                  |.||..|    |:|                  .|.|:  ..:.
 Worm   386 GLCRRFEAQMLPCLGEIVQNLLGSGDWIKIDIVYSLITAIAVKTETAKSGVTATNPLVDINDFFI 450

  Fly   462 TCFTQH-------SQVMIPEVLRFVRRAQQLQLTPESDLKAILLKDAIYNA----VGQAAFHFFN 515
            |....|       :.::..:.|:|....:: ||.||..:.||...||:.::    :.:.|.:...
 Worm   451 TQVATHLNADVNQTPILKADALKFAVTFRK-QLAPEHLMTAIKSADALLSSNTPILHKYAAYAIE 514

  Fly   516 KLDFGAWLTSQLLAELR--VEALNF---RILRRRIIWLVGHWVGVQLPRELR----PLAYEACLH 571
            |:         |||:..  ..|.|.   .||:..:         ....::.:    |...:|.|.
 Worm   515 KI---------LLADSNKIFSAQNLPVSSILQNLV---------TAFDKDAKAQNSPYLIKAILR 561

  Fly   572 LLRPQEDMPTRLAAARTLNL--LIDDFEFMP-EAFHPYFPSLFEALFLLLHEAGECDTKIVVLGT 633
            ::...:|...|.|.|..:.|  |::.....| ::.|.:|  |||.:.:|:       ||...:|.
 Worm   562 IIVILDDDTIRHADAIAVKLAQLVESATKNPADSVHTHF--LFETICVLI-------TKTRTIGA 617

  Fly   634 MTLLVEKMSEYIEPQALQFIAYLPLLWRESEEHDLLRCA--IIGTLEQ--LVRTIR-DVPEPMKP 693
            .          ::.|.|..|   .:::||..| ||:..|  |.|.|..  :.|... |...|..|
 Worm   618 S----------LDAQLLPLI---EVIFREDLE-DLIPYALQITGVLVSSCIARNSSIDQFSPFLP 668

  Fly   694 FLYSVIELSTDLQQPSHVYLIEDGIMLWLAVIGNSTALTPELLGLCDHLLPI--IEMSSENLRTV 756
            ||.|.                    .||.     .:|..|..|.:.:.:|.:  ..:.|||...:
 Worm   669 FLLSE--------------------RLWA-----RSANVPAALSVLEVILSVNAQRVVSENSGLI 708

  Fly   757 LQLIHAYILLDAQAYLSRYGEGFVAYCVRSFEDIRVEGIIAMLRIIETCLKTDAALGLRLVRPAL 821
            |.  |...||.::. |.:||....|..:.|.|  ..|| .||..::.|
 Worm   709 LS--HLARLLGSKT-LDQYGFQLAATILPSIE--HFEG-SAMTFVLNT----------------- 750

  Fly   822 PFVFQQVCLKQEYPMTMGWYLTIVARTLL-------------IDQSVFMSVVQQLPQADALARIL 873
              :|::| ...:.|..|..::..:.|..:             |...:|..:::::
 Worm   751 --MFRRV-QSSKTPKFMKLFIVFLCRFTIARSAQDLVQSCENIQTGMFGMLIEKV---------- 802

  Fly   874 DVWIEMFPMVPDTHAEKRKLFCLAFASIFGSNELLLARLPHILQLVDETLGE--VMDKQYAATEE 936
             |.|::..:...|...::::..:...::             :..:..:.:|:  ::..:.|...|
 Worm   803 -VCIDLPGLKQTTTGPEKRIIAIGMGNL-------------LADVTQQLVGQYGILSYEVAMLLE 853

  Fly   937 GASQATPRFYDSLVIHDEHE 956
            .||.:     |..|:..|.|
 Worm   854 AASAS-----DRAVLSPEEE 868

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Impbeta11	NP_788357.1	CSE1	23..>768	CDD:227944	180/852 (21%)
		IBN_N	42..120	CDD:197981	24/77 (31%)
xpo-2	NP_490716.1	CSE1	3..799	CDD:227944	199/958 (21%)
		Cse1	150..513	CDD:369909	69/407 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5657
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900