Protein Alignment CG8207 and EIF2B3

DIOPT Version :9

• Sequence 1: NP_611051.2
• Gene: CG8207 / 36730
• FlyBaseID: FBgn0034035
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: XP_016858234.1
• Gene: EIF2B3 / 8891
• HGNCID: 3259
• Length: 457
• Species: Homo sapiens
• Alignment Length: 497
• Identity: 92/497 - (18%)
• Similarity: 155/497 - (31%)
• Gaps: 195/497 - (39%)

  Fly     5 VILIGGPQKGTRFRPLSLDTPKPLFPLAGRPLIAHHIEACAQLPDIREILIIGYYPQTQME--GF 67
            |:.:||   |:|...|:...||||.|:..:|||                    :||...:|  ||
Human     7 VMAVGG---GSRMTDLTSSIPKPLLPVGNKPLI--------------------WYPLNLLERVGF 48

  Fly    68 -------VGDMQ-ALYSSSNINIR----YLQEFTALGTAGGMYHFRDQIRAGNPRAFFVLNGDVC 120
                   ..|:| ||.:...:.::    .:.:...:|||..:.:...:::..    ..||:.|:.
Human    49 EEVIVVTTRDVQKALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTD----VLVLSCDLI 109

  Fly   121 ADFPLQELCDFHEKRPASALVTI-------------------------------------MSTEA 148
            .|..|.|:.|......||..:.:                                     |:.||
Human   110 TDVALHEVVDLFRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEA 174

  Fly   149 TRQQSL----------------------HYGCLV-----FDRSSGAVS--------HYVEKPSSY 178
            ...:.|                      |..||.     |...:|:::        :.|.|..|.
Human   175 DLDEELVIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSS 239

  Fly   179 VSTFINCG----------VYVCSMDIFTVLAQIFHSRGQEY-SCQAFCNGNGNGNGREQGHIKWE 232
            .|:  ..|          ..:.|:||::.:.:........| :|...|.|:           :||
Human   240 ASS--QQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGD-----------RWE 291

  Fly   233 --------------QEVLTPLAGTDKLFAMPVPNWWSQLKTAGSAIYANRHYLGLYKKTHPERLA 283
                          :|.|.                 |::.|.|..:.|||..        |:.|
Human   292 DLSRSQVRCYVHIMKEGLC-----------------SRVSTLGLYMEANRQV--------PKLL- 330

  Fly   284 NVGIKRGEGDGSLICTVHPDVYVHPSATVHHSAVLGPNVAIGPGVTIGPGVRIRESIVLEQAQIL 348
                       |.:|...|.  ||.||.:....::|.:..|||...||....|:.|::.....|.
Human   331 -----------SALCPEEPP--VHSSAQIVSKHLVGVDSLIGPETQIGEKSSIKRSVIGSSCLIK 382

  Fly   349 DHTLVLHSIVGRGSTIGAWARVEGTPSDPDPNKPFAKMENPP 390
            |...:.:.::....|:     .||..|..:......|.:.||
Human   383 DRVTITNCLLMNSVTV-----EEGVMSSLESLSTHQKRKEPP 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8207	NP_611051.2	GCD1	1..366	CDD:224129	86/471 (18%)
		M1P_guanylylT_A_like_N	4..270	CDD:133050	66/375 (18%)
		LbetaH	306..372	CDD:294107	15/65 (23%)
EIF2B3	XP_016858234.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810