DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8207 and gmppaa

DIOPT Version :9

Sequence 1:	NP_611051.2	Gene:	CG8207 / 36730	FlyBaseID:	FBgn0034035	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	XP_005167533.1	Gene:	gmppaa / 431743	ZFINID:	ZDB-GENE-040704-37	Length:	427	Species:	Danio rerio

Alignment Length:	440	Identity:	241/440 - (54%)
Similarity:	314/440 - (71%)	Gaps:	15/440 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLKAVILIGGPQKGTRFRPLSLDTPKPLFPLAGRPLIAHHIEACAQLPDIREILIIGYY-PQTQM 64
            |||||||||||||||||||||.:.||||||:||.|::.||||||::||:::|||:||:| |..::
Zfish     1 MLKAVILIGGPQKGTRFRPLSFEVPKPLFPVAGVPMLQHHIEACSKLPNMKEILLIGFYQPNEEL 65

  Fly    65 EGFVGDMQALYSSSNINIRYLQEFTALGTAGGMYHFRDQIRAGNPRAFFVLNGDVCADFPLQELC 129
            ..|:...|   ....|:||||||:.||||.||:|||||||.:|.|.||||:|.|||::|||.|:.
Zfish    66 NRFLSCAQ---QDFKISIRYLQEYAALGTGGGIYHFRDQILSGGPDAFFVMNADVCSEFPLPEML 127

  Fly   130 DFHEKRPASALVTIMSTEATRQQSLHYGCLVFDRSSGAVSHYVEKPSSYVSTFINCGVYVCSMDI 194
            ||.::...:....|:.|.|.|:|||:|||:|.:..:..|.||||||.::||..||||:|:.:.:|
Zfish   128 DFQKEHGDTYSFVILGTTANRKQSLNYGCIVENEQTDEVLHYVEKPGTFVSDIINCGIYLFTPEI 192

  Fly   195 FTVLAQIFHSRGQEYSCQAFCNGNGNGNGREQGH-IKWEQEVLTPLAGTDKLFAMPVPNWWSQLK 258
            |..:..:|....||....:: .|....||..:.. |:.||::.|.|||..||:......:|||:|
Zfish   193 FQHIGSVFQKNQQEMLLYSY-EGEEQSNGWHRAEVIRLEQDIFTALAGQGKLYVYKTDRFWSQIK 256

  Fly   259 TAGSAIYANRHYLGLYKKTHPERLANVGIKRGEGDGSLICTVHPDVYVHPSATVHHSAVLGPNVA 323
            :|||||||:|.||..|.||||||||.    ..||...    ...:||:||:|.:..:|||||||:
Zfish   257 SAGSAIYASRLYLNQYHKTHPERLAT----NTEGGAK----TRGNVYIHPTANIDPTAVLGPNVS 313

  Fly   324 IGPGVTIGPGVRIRESIVLEQAQILDHTLVLHSIVGRGSTIGAWARVEGTPSDPDPNKPFAKMEN 388
            ||.|||||.|||:||||:|..|.:.||:.||:||||..||||.|||||||||||:||.|:||:::
Zfish   314 IGTGVTIGAGVRVRESIILHGATLQDHSCVLNSIVGWESTIGKWARVEGTPSDPNPNDPYAKIDS 378

  Fly   389 PPLFNNEGKLNPSITILGCFVQVPAEKILLNSIVLPHKELSRSFKNEIIL 438
            ..|| .:|||.||||||||.|.:|:|.|:|||||||||:|:|||||:|||
Zfish   379 ETLF-RDGKLTPSITILGCNVNIPSEVIILNSIVLPHKDLNRSFKNQIIL 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8207	NP_611051.2	GCD1	1..366	CDD:224129	189/366 (52%)
		M1P_guanylylT_A_like_N	4..270	CDD:133050	134/267 (50%)
		LbetaH	306..372	CDD:294107	42/65 (65%)
gmppaa	XP_005167533.1	GCD1	1..356	CDD:224129	189/366 (52%)
		M1P_guanylylT_A_like_N	4..268	CDD:133050	134/267 (50%)
		LbetaH	296..362	CDD:294107	42/65 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582030
Domainoid	1	1.000	235	1.000	Domainoid score	I2299
eggNOG	1	0.900	-	-		E1_COG1208
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8346
Inparanoid	1	1.050	468	1.000	Inparanoid score	I1497
OMA	1	1.010	-	-		QHG54613
OrthoDB	1	1.010	-	-		D336231at33208
OrthoFinder	1	1.000	-	-		FOG0000664
OrthoInspector	1	1.000	-	-		otm26110
orthoMCL	1	0.900	-	-		OOG6_103587
Panther	1	1.100	-	-	LDO	PTHR22572
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1723
SonicParanoid	1	1.000	-	-		X2857
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800