Protein Alignment CG8207 and GMPPB

DIOPT Version :9

• Sequence 1: NP_611051.2
• Gene: CG8207 / 36730
• FlyBaseID: FBgn0034035
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_037466.3
• Gene: GMPPB / 29925
• HGNCID: 22932
• Length: 387
• Species: Homo sapiens
• Alignment Length: 444
• Identity: 140/444 - (31%)
• Similarity: 200/444 - (45%)
• Gaps: 79/444 - (17%)

  Fly     2 LKAVILIGGPQKGTRFRPLSLDTPKPLFPLAGRPLIAHHIEACAQLPDIREILIIGYYPQTQMEG 66
            :||:||:||  .|||.|||:|.|||||.....:|::.|.:||.|.......||.:.|..|...:
Human     1 MKALILVGG--YGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQVLEK- 62

  Fly    67 FVGDMQALYSSSNINIRYLQEFTALGTAGGMYHFRDQI-RAGNPRAFFVLNGDVCADFPLQELCD 130
               :|:|......|.|....|...|||||.:...||.: ...:|  |||||.||..|||.|.:..
Human    63 ---EMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSETADP--FFVLNSDVICDFPFQAMVQ 122

  Fly   131 FHEK--RPASALVTIMSTEATRQQSLHYGCLVFDRSSGAVSHYVEKPSSYVSTFINCGVYVCSMD 193
            ||..  :..|.|||.:      ::...||.:|.:..:|.:..:||||..:||..||.|:|:.|.
Human   123 FHRHHGQEGSILVTKV------EEPSKYGVVVCEADTGRIHRFVEKPQVFVSNKINAGMYILSP- 180

  Fly   194 IFTVLAQIFHSRGQEYSCQAFCNGNGNGNGREQGHIKWEQEVLTPLAGTDKLFAMPVPNWWSQLK 258
              .||.:|   :.|..|.                    |:||...:|...:|:||.:..:|..:.
Human   181 --AVLQRI---QLQPTSI--------------------EKEVFPIMAKEGQLYAMELQGFWMDIG 220

  Fly   259 TAGSAIYANRHYLGLYKKTHPERLANVGIKRGEGDGSLICTVHPDVYVHPSATVHHSAVLGPNVA 323
            .....:.....:|...::..||||.:       |.|     :..:|.|.|||.:..:..:||||:
Human   221 QPKDFLTGMCLFLQSLRQKQPERLCS-------GPG-----IVGNVLVDPSARIGQNCSIGPNVS 273

  Fly   324 IGPGVTIGPGVRIRESIVLEQAQILDHTLVLHSIVG----RGSTIGAWARVEGTPSD-----PDP 379
            :||||.:..||.||...||..|:|..|:.:...|||    .|..:..||.:.|....     ||.
Human   274 LGPGVVVEDGVCIRRCTVLRDARIRSHSWLESCIVGWRCRVGQWVSLWAGLGGERGGECACLPDK 338

  Fly   380 NKPF--AKMENPPLFNNEGKLNPSITILGCFVQVPAEKILLNSIVLPHKELSRS 431
            ..|.  .:|||             :|:||..|.|..|..|..:.|||||.:..|
Human   339 AYPLLEVRMEN-------------VTVLGEDVIVNDELYLNGASVLPHKSIGES 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8207	NP_611051.2	GCD1	1..366	CDD:224129	118/370 (32%)
		M1P_guanylylT_A_like_N	4..270	CDD:133050	84/268 (31%)
		LbetaH	306..372	CDD:294107	27/69 (39%)
GMPPB	NP_037466.3	M1P_guanylylT_B_like_N	1..233	CDD:133047	85/271 (31%)
		LbetaH	255..361	CDD:412191	39/118 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1057
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D336231at33208
OrthoFinder	1	1.000	-	-		FOG0000664
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.770