Protein Alignment Gmppa and mpg2

DIOPT Version :10

• Sequence 1: NP_611051.2
• Gene: Gmppa / 36730
• FlyBaseID: FBgn0034035
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_596551.1
• Gene: mpg2 / 2539751
• PomBaseID: SPBC13G1.02
• Length: 414
• Species: Schizosaccharomyces pombe
• Alignment Length: 445
• Identity: 172/445 - (38%)
• Similarity: 260/445 - (58%)
• Gaps: 45/445 - (10%)

  Fly     4 AVILIGGPQKGTRFRPLSLDTPKPLFPLAGRPLIAHHIEACAQLPDIREILIIGYYPQTQMEGFV 68
            ||||:|||.:||||||||.|.|||||.:.||.:|.||:.|.:::..::::.::|:|.::..:.|:
pombe     5 AVILVGGPSRGTRFRPLSFDVPKPLFKIGGREMIYHHLAALSKIESVKDVFLVGFYDESVFKDFI 69

  Fly    69 GDMQALYSSSNINIRYLQEFTALGTAGGMYHFRDQIRAGNPRAFFVLNGDVCADFPLQELCDFHE 133
            .::.:.:.|.| .|:||:|:..|||.||:|||||||..|:....||::.|||..||||||.:.|.
pombe    70 NEVASHFPSFN-RIKYLREYNCLGTGGGLYHFRDQILKGHTSNVFVMHADVCCSFPLQELLNVHH 133

  Fly   134 KRPASALVTIMSTEATRQQSLHYGCLVFDRSSGAVSHYVEKPSSYVSTFINCGVYVCSMDIFTVL 198
            ::  .||||:|:|:.:::.:.::||||.:.|:|.|.|||:|||||:|..|:||:|:....||..:
pombe   134 EK--KALVTLMATKVSKEDASNFGCLVEEPSTGRVLHYVDKPSSYLSNIISCGIYIFDASIFDEI 196

  Fly   199 AQIFHSRGQEYSCQAFCNGNGNGNGREQGHIKWEQEVLTPLA--GTDKLFAMPVPNWWSQLKTAG 261
            .:.:..|.:|...|......|     .:.::..|.:||.||.  .:..::|...|.:|.|:||||
pombe   197 KKAYERRLEEVEKQLRSLDEG-----MEDYLSLETDVLAPLCSDSSKAIYAYNTPEFWRQIKTAG 256

  Fly   262 SAIYANRHYLGLYKKTHPERLANVGIKRGEGDGSLICTVHPD--------VYVHPSATVHHSAVL 318
            ||:.||..|  |.|..|              ||:|   ..||        |::||:|.|...|.:
pombe   257 SAVPANSLY--LQKAYH--------------DGTL---PKPDTEAEIIQPVFIHPNAIVSKGAKI 302

  Fly   319 GPNVAIGPGVTIGPGVRIRESIVLEQAQILDHTLVLHSIVGRGSTIGAWARVEGTPSDPDPNKPF 383
            ||||:||..|.|..|.|||.||:.|..:|..:.:|||||:.|...||.|:||||:|:.|
pombe   303 GPNVSIGARVRIEDGARIRNSIIQEDCEISANAVVLHSILSRHCKIGKWSRVEGSPTLP------ 361

  Fly   384 AKMENPPLFNNEGKLNPSITILGCFVQVPAEKILLNSIVLPHKELSRSFKNEIIL 438
             ...:..:..|..|:. :||::|....|..|..:.|.:||||||:......||::
pombe   362 -SQHSTTIMRNSVKVQ-AITVMGADCIVHDEVRVQNCLVLPHKEIKVGLVGEIVM 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gmppa	NP_611051.2	M1P_guanylylT_A_like_N	4..270	CDD:133050	110/267 (41%)
		LbetaH	306..372	CDD:469633	32/65 (49%)
mpg2	NP_596551.1	M1P_guanylylT_A_like_N	5..265	CDD:133050	110/267 (41%)
		LbetaH	289..357	CDD:469633	33/67 (49%)
		LbetaH	324..>405	CDD:469633	32/88 (36%)