DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8207 and SPBC13G1.02

DIOPT Version :9

Sequence 1:	NP_611051.2	Gene:	CG8207 / 36730	FlyBaseID:	FBgn0034035	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_596551.1	Gene:	SPBC13G1.02 / 2539751	PomBaseID:	SPBC13G1.02	Length:	414	Species:	Schizosaccharomyces pombe

Alignment Length:	445	Identity:	172/445 - (38%)
Similarity:	260/445 - (58%)	Gaps:	45/445 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 AVILIGGPQKGTRFRPLSLDTPKPLFPLAGRPLIAHHIEACAQLPDIREILIIGYYPQTQMEGFV 68
            ||||:|||.:||||||||.|.|||||.:.||.:|.||:.|.:::..::::.::|:|.::..:.|:
pombe     5 AVILVGGPSRGTRFRPLSFDVPKPLFKIGGREMIYHHLAALSKIESVKDVFLVGFYDESVFKDFI 69

  Fly    69 GDMQALYSSSNINIRYLQEFTALGTAGGMYHFRDQIRAGNPRAFFVLNGDVCADFPLQELCDFHE 133
            .::.:.:.|.| .|:||:|:..|||.||:|||||||..|:....||::.|||..||||||.:.|.
pombe    70 NEVASHFPSFN-RIKYLREYNCLGTGGGLYHFRDQILKGHTSNVFVMHADVCCSFPLQELLNVHH 133

  Fly   134 KRPASALVTIMSTEATRQQSLHYGCLVFDRSSGAVSHYVEKPSSYVSTFINCGVYVCSMDIFTVL 198
            ::  .||||:|:|:.:::.:.::||||.:.|:|.|.|||:|||||:|..|:||:|:....||..:
pombe   134 EK--KALVTLMATKVSKEDASNFGCLVEEPSTGRVLHYVDKPSSYLSNIISCGIYIFDASIFDEI 196

  Fly   199 AQIFHSRGQEYSCQAFCNGNGNGNGREQGHIKWEQEVLTPLA--GTDKLFAMPVPNWWSQLKTAG 261
            .:.:..|.:|...|......|     .:.::..|.:||.||.  .:..::|...|.:|.|:||||
pombe   197 KKAYERRLEEVEKQLRSLDEG-----MEDYLSLETDVLAPLCSDSSKAIYAYNTPEFWRQIKTAG 256

  Fly   262 SAIYANRHYLGLYKKTHPERLANVGIKRGEGDGSLICTVHPD--------VYVHPSATVHHSAVL 318
            ||:.||..|  |.|..|              ||:|   ..||        |::||:|.|...|.:
pombe   257 SAVPANSLY--LQKAYH--------------DGTL---PKPDTEAEIIQPVFIHPNAIVSKGAKI 302

  Fly   319 GPNVAIGPGVTIGPGVRIRESIVLEQAQILDHTLVLHSIVGRGSTIGAWARVEGTPSDPDPNKPF 383
            ||||:||..|.|..|.|||.||:.|..:|..:.:|||||:.|...||.|:||||:|:.|
pombe   303 GPNVSIGARVRIEDGARIRNSIIQEDCEISANAVVLHSILSRHCKIGKWSRVEGSPTLP------ 361

  Fly   384 AKMENPPLFNNEGKLNPSITILGCFVQVPAEKILLNSIVLPHKELSRSFKNEIIL 438
             ...:..:..|..|:. :||::|....|..|..:.|.:||||||:......||::
pombe   362 -SQHSTTIMRNSVKVQ-AITVMGADCIVHDEVRVQNCLVLPHKEIKVGLVGEIVM 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8207	NP_611051.2	GCD1	1..366	CDD:224129	148/371 (40%)
		M1P_guanylylT_A_like_N	4..270	CDD:133050	110/267 (41%)
		LbetaH	306..372	CDD:294107	32/65 (49%)
SPBC13G1.02	NP_596551.1	GCD1	5..404	CDD:224129	169/433 (39%)
		M1P_guanylylT_A_like_N	5..265	CDD:133050	110/267 (41%)
		LbetaH	289..357	CDD:294107	33/67 (49%)
		LbetaH	324..>405	CDD:294107	32/88 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	202	1.000	Domainoid score	I648
eggNOG	1	0.900	-	-		E1_COG1208
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8346
Inparanoid	1	1.050	309	1.000	Inparanoid score	I583
OMA	1	1.010	-	-		QHG54613
OrthoFinder	1	1.000	-	-		FOG0000664
OrthoInspector	1	1.000	-	-		oto100816
orthoMCL	1	0.900	-	-		OOG6_103587
Panther	1	1.100	-	-	LDO	PTHR22572
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1723
SonicParanoid	1	1.000	-	-		X2857
TreeFam	1	0.960	-	-
	14	13.860