DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8207 and eif-2Bepsilon

DIOPT Version :9

Sequence 1:	NP_611051.2	Gene:	CG8207 / 36730	FlyBaseID:	FBgn0034035	Length:	438	Species:	Drosophila melanogaster
Sequence 2:	NP_495841.1	Gene:	eif-2Bepsilon / 174387	WormBaseID:	WBGene00008428	Length:	666	Species:	Caenorhabditis elegans

Alignment Length:	115	Identity:	28/115 - (24%)
Similarity:	45/115 - (39%)	Gaps:	20/115 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   322 VAIGPGVTIGPGVRIRESIVLEQAQILDHTLVLHSIVGRGSTIGAWARVEGTPSDPDPNKPFAKM 386
            |.:|....|.....||.|.:....:|...|.:..|::|:...||....:|           :|.:
Worm   329 VCLGVKTDIAYDAFIRNSCIGAHTEISSKTRITSSMIGKNCKIGENCVIE-----------YAFI 382

  Fly   387 ENPPLFNNEGKLNPSITILGCFVQVPAEKILLNSIVLPHKELSRSFKNEI 436
            .:..:..| |...|..:|:|..|..|.|        ||:.:.:..|||.|
Worm   383 GDDVVIPN-GAHIPKESIIGNGVMYPKE--------LPNIQNTAIFKNAI 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8207	NP_611051.2	GCD1	1..366	CDD:224129	11/43 (26%)
		M1P_guanylylT_A_like_N	4..270	CDD:133050
		LbetaH	306..372	CDD:294107	12/49 (24%)
eif-2Bepsilon	NP_495841.1	Glyco_tranf_GTA_type	19..218	CDD:386096
		LbetaH	331..404	CDD:381831	18/84 (21%)
		W2_eIF2B_epsilon	484..655	CDD:211396
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810