Protein Alignment CG8207 and Eif2b3

DIOPT Version :9

• Sequence 1: NP_611051.2
• Gene: CG8207 / 36730
• FlyBaseID: FBgn0034035
• Length: 438
• Species: Drosophila melanogaster
• Sequence 2: NP_001104747.1
• Gene: Eif2b3 / 108067
• MGIID: 1313286
• Length: 452
• Species: Mus musculus
• Alignment Length: 506
• Identity: 87/506 - (17%)
• Similarity: 171/506 - (33%)
• Gaps: 145/506 - (28%)

  Fly     5 VILIGGPQKGTRFRPLSLDTPKPLFPLAGRPLIAHHIEACAQLPDIREILIIGYYPQTQME--GF 67
            |:.:||   |:|...|:...||||.|:..:|||                    :||...:|  ||
Mouse     7 VMAVGG---GSRMTDLTSSIPKPLLPVGNKPLI--------------------WYPLNLLERVGF 48

  Fly    68 -------VGDMQALYSSS-----NINIRYLQEFTALGTAGGMYHFRDQIRAGNPRAFFVLNGDVC 120
                   ..|:|....:.     .::|..:.:...:|||..:.|...:::..    ..||:.|:.
Mouse    49 EEVIVVTTKDVQKALCAEFKMKMKLDIVCIPDEADMGTADSLRHIYPKLKTD----VLVLSCDLI 109

  Fly   121 ADFPLQELCDFHEKRPASALVTI-------------------------------------MSTEA 148
            .|..|.|:.|......||..:.:                                     |:.||
Mouse   110 TDVALHEVVDLFRAYDASLAMLMRKGQESIEPVPGQKGKKKPVEQRDFIGVDSTGKRLLFMANEA 174

  Fly   149 TRQQSL-------------HYGCLVFDRSSGAVSHYVEKPSSYVSTFI--NCGVYVCSMDIFTVL 198
            ...:.|             |:       .:|.|..::.....||..|:  |..:.....::...|
Mouse   175 DLDEELVIKGSILQKHPRIHF-------HTGLVDAHLYCLKKYVVDFLMENRSITSIRSELIPYL 232

  Fly   199 AQIFHSRGQEYSCQAFCNGNGNGNGREQGHIKWE---QEVLTPLAGTDKLFAMPVPNWWSQLK-- 258
            .:...|.......|         ..:|:...|.|   .::.:.:...|.|...|....|:..:
Mouse   233 VRKQFSSASSQQRQ---------EDKEEDLKKKELKSLDIYSFIKKDDTLTLAPYDACWNAFRGD 288

  Fly   259 ----TAGSAIYANRHYLGLYKKTHPERLANVGI--KRGEGDGSLICTVHP-DVYVHPSATVHHSA 316
                .:.|.:   |.|:.:.|:....|::.:|:  :.......|:..:.| :..:|.||.:.:..
Mouse   289 KWEDLSRSQV---RCYVHIMKEGLCSRVSTLGLYMEANRQVPKLLSVLCPEESMIHSSAQIVNKH 350

  Fly   317 VLGPNVAIGPGVTIGPGVRIRESIVLEQAQILDHTLVLHSIVGRGSTIGAWARVEGTPSDPDPNK 381
            ::|.:..|||...||....|:.|::.....|.|.|.:.:.::....|:...:.:.|:
Mouse   351 LIGADSLIGPDTQIGEKSSIKHSVIGSSCVIRDRTSITNCLLMNSVTVEEGSSIHGS-------- 407

  Fly   382 PFAKMENPPLFNNEGKLNPSITILGCFV----QVPAEKILLNSIVLPHKEL 428
                     :..|...:.....|..|.|    ::.|:...:|.:::.:.:|
Mouse   408 ---------VICNNAVIETGAEIKNCLVGSGQRIEAKAKRMNEVIVGNDQL 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8207	NP_611051.2	GCD1	1..366	CDD:224129	79/438 (18%)
		M1P_guanylylT_A_like_N	4..270	CDD:133050	58/339 (17%)
		LbetaH	306..372	CDD:294107	15/65 (23%)
Eif2b3	NP_001104747.1	eIF-2B_gamma_N	3..212	CDD:133041	43/238 (18%)
		GCD1	4..447	CDD:224129	86/502 (17%)
		LbH_eIF2B_gamma_C	357..437	CDD:100057	17/96 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810