Protein Alignment Cdk5 and SLT2

DIOPT Version :10

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_011895.1
• Gene: SLT2 / 856425
• SGDID: S000001072
• Length: 484
• Species: Saccharomyces cerevisiae
• Alignment Length: 320
• Identity: 115/320 - (35%)
• Similarity: 173/320 - (54%)
• Gaps: 55/320 - (17%)

  Fly     2 QKYDKMEKIGEGTYGTVFKGRNRDTME--IVALKRVRLDEDDEGVPSSALREICLLKELK-HKNI 63
            :::..:::||.|.||.|...|..:..|  .||:|:|........:...:|||:.||:..: ||||
Yeast    21 KRFQLIKEIGHGAYGIVCSARFAEAAEDTTVAIKKVTNVFSKTLLCKRSLRELKLLRHFRGHKNI 85

  Fly    64 VRLIDVLHSDKKLTLVFEHCDQDLKKYFD-SLNG--------EIDM------------AVCRSFM 107
            ..|.|:                |:..|.| |:||        |.||            |..:||.
Yeast    86 TCLYDM----------------DIVFYPDGSINGLYLYEELMECDMHQIIKSGQPLTDAHYQSFT 134

  Fly   108 LQLLRGLAFCHSHNVLHRDLKPQNLLINKNGELKLADFGLARAFG-IPV---KCYSAEVVTLWYR 168
            .|:|.||.:.||.:||||||||.|||:|.:.:||:.||||||.:. .||   :..:..|.|.|||
Yeast   135 YQILCGLKYIHSADVLHRDLKPGNLLVNADCQLKICDFGLARGYSENPVENSQFLTEYVATRWYR 199

  Fly   169 PPDVLFGAKLYTTSIDMWSAGCILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWP--GVS 231
            .|:::...:.||.:||:|||||||||.. .|:|:|.|.|.::||.:|.:|||||.:::..  |..
Yeast   200 APEIMLSYQGYTKAIDVWSAGCILAEFL-GGKPIFKGKDYVNQLNQILQVLGTPPDETLRRIGSK 263

  Fly   232 HLSDYV----ALPSFPAITSWSQLVPRLNSKGRDLLQKLLICRPNQRISAEAAMQHPYFT 287
            ::.||:    .:|..|.:    .|.|..||:..|||:::|...|.:||:.:.|::|||.:
Yeast   264 NVQDYIHQLGFIPKVPFV----NLYPNANSQALDLLEQMLAFDPQKRITVDEALEHPYLS 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344	114/316 (36%)
SLT2	NP_011895.1	STKc_MPK1	22..355	CDD:173750	115/319 (36%)