Protein Alignment Cdk5 and cdk2

DIOPT Version :9

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_001008136.1
• Gene: cdk2 / 493498
• XenbaseID: XB-GENE-1001990
• Length: 297
• Species: Xenopus tropicalis
• Alignment Length: 296
• Identity: 174/296 - (58%)
• Similarity: 224/296 - (75%)
• Gaps: 12/296 - (4%)

  Fly     1 MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVR 65
            |:.:.|:|||||||||.|:|.|||:|.||||||::|||.:.|||||:|:|||.|||||.|.|||:
 Frog     1 MENFQKVEKIGEGTYGVVYKARNRETGEIVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVK 65

  Fly    66 LIDVLHSDKKLTLVFEHCDQDLKKYFDSLN-GEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLKP 129
            |:||:|::.||.||||..:|||||:.|..| ..|.:|:.:|::.|||:||||||||.||||||||
 Frog    66 LLDVIHTENKLYLVFEFLNQDLKKFMDGSNISGISLALVKSYLFQLLQGLAFCHSHRVLHRDLKP 130

  Fly   130 QNLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCILAE 194
            ||||||..|.:||||||||||||:||:.|:.||||||||.|::|.|.|.|:|::|:||.|||.||
 Frog   131 QNLLINSEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKFYSTAVDIWSLGCIFAE 195

  Fly   195 LADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVALPSFPAITSW-----SQLVPR 254
            :. ..|.||||...:|||.:|||.||||:|.|||||:.:.||.:  :||   .|     |::||.
 Frog   196 MI-TRRALFPGDSEIDQLFRIFRTLGTPDEVSWPGVTTMPDYKS--TFP---KWVRQDFSKVVPP 254

  Fly   255 LNSKGRDLLQKLLICRPNQRISAEAAMQHPYFTDSS 290
            |:..|||||.::|....|:||||:||:.|.:|.|.|
 Frog   255 LDDDGRDLLAQMLQYDSNKRISAKAALTHAFFRDVS 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	PLN00009	1..288	CDD:177649	172/292 (59%)
		STKc_CDK5	3..286	CDD:143344	170/288 (59%)
cdk2	NP_001008136.1	STKc_CDK2_3	3..286	CDD:270844	170/288 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1010560at2759
OrthoFinder	1	1.000	-	-		FOG0000411
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R185
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.040