Protein Alignment Cdk5 and Cdk2

DIOPT Version :9

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_001163666.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Alignment Length: 294
• Identity: 139/294 - (47%)
• Similarity: 195/294 - (66%)
• Gaps: 3/294 - (1%)

  Fly     1 MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVR 65
            :..:.:.|||||||||.|:|.|:..|.:.||||::||:.:.|||||:|:|||.|||.|||.|:|:
  Fly     5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQ 69

  Fly    66 LIDVLHSDKKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLKPQ 130
            |.||:.|...|.::||:.:.||||..|.........:.:|:|.|:|..:.|||::.:||||||||
  Fly    70 LFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQ 134

  Fly   131 NLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCILAEL 195
            |||::..|::|||||||||||.:|::.|:.||||||||.|::|.|.|.|:|.:|:||.|||.:|:
  Fly   135 NLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEM 199

  Fly   196 ADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVALPSFPAITSWSQLVPRLNSKGR 260
            . ..|.||||...:|||.:|||.|.||:|.:||||:.|.|:..  .||.....:...|....:..
  Fly   200 I-MRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKT--KFPRWEGTNMPQPITEHEAH 261

  Fly   261 DLLQKLLICRPNQRISAEAAMQHPYFTDSSSSGH 294
            :|:..:|...||.||||:.|:||.||.:.....|
  Fly   262 ELIMSMLCYDPNLRISAKDALQHAYFRNVQHVDH 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	PLN00009	1..288	CDD:177649	138/286 (48%)
		STKc_CDK5	3..286	CDD:143344	136/282 (48%)
Cdk2	NP_001163666.1	PLN00009	5..293	CDD:177649	138/290 (48%)
		STKc_CDK1_CdkB_like	8..287	CDD:270829	136/281 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442462
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1010560at2759
OrthoFinder	1	1.000	-	-		FOG0000411
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100334
Panther	1	1.100	-	-	P	PTHR24056
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R185
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.880