Protein Alignment Cdk5 and Cdk2

DIOPT Version :10

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_524420.1
• Gene: Cdk2 / 42453
• FlyBaseID: FBgn0004107
• Length: 314
• Species: Drosophila melanogaster
• Alignment Length: 294
• Identity: 139/294 - (47%)
• Similarity: 195/294 - (66%)
• Gaps: 3/294 - (1%)

  Fly     1 MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVR 65
            :..:.:.|||||||||.|:|.|:..|.:.||||::||:.:.|||||:|:|||.|||.|||.|:|:
  Fly     5 LDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQ 69

  Fly    66 LIDVLHSDKKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLKPQ 130
            |.||:.|...|.::||:.:.||||..|.........:.:|:|.|:|..:.|||::.:||||||||
  Fly    70 LFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQ 134

  Fly   131 NLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCILAEL 195
            |||::..|::|||||||||||.:|::.|:.||||||||.|::|.|.|.|:|.:|:||.|||.:|:
  Fly   135 NLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEM 199

  Fly   196 ADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVALPSFPAITSWSQLVPRLNSKGR 260
            . ..|.||||...:|||.:|||.|.||:|.:||||:.|.|:..  .||.....:...|....:..
  Fly   200 I-MRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKT--KFPRWEGTNMPQPITEHEAH 261

  Fly   261 DLLQKLLICRPNQRISAEAAMQHPYFTDSSSSGH 294
            :|:..:|...||.||||:.|:||.||.:.....|
  Fly   262 ELIMSMLCYDPNLRISAKDALQHAYFRNVQHVDH 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344	136/282 (48%)
Cdk2	NP_524420.1	STKc_CDK1_CdkB_like	8..287	CDD:270829	136/281 (48%)