Protein Alignment Cdk5 and cdk2

DIOPT Version :9

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_998571.1
• Gene: cdk2 / 406715
• ZFINID: ZDB-GENE-040426-2741
• Length: 298
• Species: Danio rerio
• Alignment Length: 294
• Identity: 170/294 - (57%)
• Similarity: 219/294 - (74%)
• Gaps: 12/294 - (4%)

  Fly     1 MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVR 65
            |:.:.|:|||||||||.|:|.:|:.|.|.||||::|||.:.|||||:|:|||.|||||.|.|||:
Zfish     1 MESFQKVEKIGEGTYGVVYKAKNKVTGETVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVK 65

  Fly    66 LIDVLHSDKKLTLVFEHCDQDLKKYFDSLN-GEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLKP 129
            |.||:|::.||.||||...||||::.||.: ..|.:.:.:|::.|||:||||||||.||||||||
Zfish    66 LRDVIHTENKLYLVFEFLHQDLKRFMDSTSVSGISLPLVKSYLFQLLQGLAFCHSHRVLHRDLKP 130

  Fly   130 QNLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCILAE 194
            ||||||..||:||||||||||||:||:.|:.||||||||.|::|.|.|.|:|::|:||.|||.||
Zfish   131 QNLLINAQGEIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAE 195

  Fly   195 LADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVALPSFPAITSW-----SQLVPR 254
            :. ..|.||||...:|||.:|||.||||:|..||||:.:.||  .||||   .|     |::||.
Zfish   196 MI-TRRALFPGDSEIDQLFRIFRTLGTPDESIWPGVTSMPDY--KPSFP---KWARQDLSKVVPP 254

  Fly   255 LNSKGRDLLQKLLICRPNQRISAEAAMQHPYFTD 288
            |:..|||||.::|...||:||||:.|:.|.:|.|
Zfish   255 LDEDGRDLLGQMLTYDPNKRISAKNALVHRFFRD 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	PLN00009	1..288	CDD:177649	169/292 (58%)
		STKc_CDK5	3..286	CDD:143344	167/288 (58%)
cdk2	NP_998571.1	PLN00009	1..291	CDD:177649	170/294 (58%)
		STKc_CDK2_3	3..286	CDD:270844	167/288 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1010560at2759
OrthoFinder	1	1.000	-	-		FOG0000411
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100334
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R185
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850