Protein Alignment Cdk5 and cdc2

DIOPT Version :9

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_001342995.1
• Gene: cdc2 / 2539869
• PomBaseID: SPBC11B10.09
• Length: 297
• Species: Schizosaccharomyces pombe
• Alignment Length: 301
• Identity: 151/301 - (50%)
• Similarity: 208/301 - (69%)
• Gaps: 19/301 - (6%)

  Fly     1 MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKEL----KHK 61
            |:.|.|:|||||||||.|:|.|::.:..|||:|::||:::.|||||:|:|||.||||:    ...
pombe     1 MENYQKVEKIGEGTYGVVYKARHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVNDENNRS 65

  Fly    62 NIVRLIDVLHSDKKLTLVFEHCDQDLKKYFDSLN----GEIDMAVCRSFMLQLLRGLAFCHSHNV 122
            |.|||:|:||::.||.||||..|.|||||.|.::    ..:|..:.:.|..||:.|:.||||..:
pombe    66 NCVRLLDILHAESKLYLVFEFLDMDLKKYMDRISETGATSLDPRLVQKFTYQLVNGVNFCHSRRI 130

  Fly   123 LHRDLKPQNLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWS 187
            :|||||||||||:|.|.||||||||||:||:|::.|:.|:||||||.|:||.|::.|:|.:|:||
pombe   131 IHRDLKPQNLLIDKEGNLKLADFGLARSFGVPLRNYTHEIVTLWYRAPEVLLGSRHYSTGVDIWS 195

  Fly   188 AGCILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVALPSFPAITSWSQL- 251
            .|||.||:.... |||||...:|::.|||:|||||||:.||||:.|.||.:  :||   .|.::
pombe   196 VGCIFAEMIRRS-PLFPGDSEIDEIFKIFQVLGTPNEEVWPGVTLLQDYKS--TFP---RWKRMD 254

  Fly   252 ----VPRLNSKGRDLLQKLLICRPNQRISAEAAMQHPYFTD 288
                ||.......:||..:|:..|..||||:.|:|..|..|
pombe   255 LHKVVPNGEEDAIELLSAMLVYDPAHRISAKRALQQNYLRD 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	PLN00009	1..288	CDD:177649	150/299 (50%)
		STKc_CDK5	3..286	CDD:143344	148/295 (50%)
cdc2	NP_001342995.1	STKc_CDK1_CdkB_like	4..293	CDD:270829	148/294 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000411
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100334
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R185
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840