Protein Alignment Cdk5 and cdk-5

DIOPT Version :9

• Sequence 1: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_499783.1
• Gene: cdk-5 / 176774
• WormBaseID: WBGene00000407
• Length: 292
• Species: Caenorhabditis elegans
• Alignment Length: 290
• Identity: 214/290 - (73%)
• Similarity: 253/290 - (87%)
• Gaps: 0/290 - (0%)

  Fly     1 MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVR 65
            |..|||||||||||||||||.||:::.|||||||||||:||||||||||||||:|:||||:|:||
 Worm     1 MLNYDKMEKIGEGTYGTVFKARNKNSGEIVALKRVRLDDDDEGVPSSALREICILRELKHRNVVR 65

  Fly    66 LIDVLHSDKKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLKPQ 130
            |.||:||:.|||||||:|||||||:||||||.:|....||.||||||||:|||:|:|||||||||
 Worm    66 LYDVVHSENKLTLVFEYCDQDLKKFFDSLNGYMDAQTARSLMLQLLRGLSFCHAHHVLHRDLKPQ 130

  Fly   131 NLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCILAEL 195
            |||||.||.|||||||||||||:||:|:|||||||||||||||||||||.|||||||||||.||:
 Worm   131 NLLINTNGTLKLADFGLARAFGVPVRCFSAEVVTLWYRPPDVLFGAKLYNTSIDMWSAGCIFAEI 195

  Fly   196 ADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVALPSFPAITSWSQLVPRLNSKGR 260
            ::||||||||:||.|||.:||:.||:|:||:||.::.|.||...|.:....:|||:||.|||:||
 Worm   196 SNAGRPLFPGADVDDQLKRIFKQLGSPSEDNWPSITQLPDYKPYPIYHPTLTWSQIVPNLNSRGR 260

  Fly   261 DLLQKLLICRPNQRISAEAAMQHPYFTDSS 290
            |||||||:|.|..||.|:||::|.||.|:|
 Worm   261 DLLQKLLVCNPAGRIDADAALRHAYFADTS 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdk5	NP_477080.1	PLN00009	1..288	CDD:177649	212/286 (74%)
		STKc_CDK5	3..286	CDD:143344	209/282 (74%)
cdk-5	NP_499783.1	PLN00009	1..292	CDD:177649	214/290 (74%)
		STKc_CDK5	3..286	CDD:143344	209/282 (74%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	451	1.000	Domainoid score	I258
eggNOG	1	0.900	-	-		E1_KOG0662
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3623
Inparanoid	1	1.050	457	1.000	Inparanoid score	I884
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1010560at2759
OrthoFinder	1	1.000	-	-		FOG0000411
OrthoInspector	1	1.000	-	-		oto20168
orthoMCL	1	0.900	-	-		OOG6_100334
Panther	1	1.100	-	-	LDO	PTHR24056
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R185
SonicParanoid	1	1.000	-	-		X3829
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.860