DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8195 and SLC35A5

DIOPT Version :9

Sequence 1:	NP_611049.1	Gene:	CG8195 / 36725	FlyBaseID:	FBgn0034032	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	NP_001335834.1	Gene:	SLC35A5 / 55032	HGNCID:	20792	Length:	424	Species:	Homo sapiens

Alignment Length:	169	Identity:	39/169 - (23%)
Similarity:	67/169 - (39%)	Gaps:	42/169 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   207 LVSSTSSFFIICLAAVFPSATGDKLTITKVIAVAMNIGGVVAITMNDLHDTKMTRGVLLALFS-- 269
            ::.|.|:.:...|.|:|.:.:..::.:.|..|...|....:..|:|..  :::.:.|...|.|
Human    10 VICSLSTMYTFLLGAIFIALSSSRILLVKYSANEENKYDYLPTTVNVC--SELVKLVFCVLVSFC 72

  Fly   270 ---------AFFYAAYLVFVKRKSDTEEKVDIPLFFGFVGLWNMLLLWPIFFILHFTKIETFELP 325
                     ...||::    |..||. .|..||.|..|  |.|::    :|::|.:.
Human    73 VIKKDHQSRNLKYASW----KEFSDF-MKWSIPAFLYF--LDNLI----VFYVLSYL-------- 118

  Fly   326 SQGQFALLFLNGLVGT-------VLSEAL-WL-WGCFLT 355
             |...|::|.|..:.|       ||...| |: |...||
Human   119 -QPAMAVIFSNFSIITTALLFRIVLKRRLNWIQWASLLT 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8195	NP_611049.1	2A78	153..399	CDD:273359	39/169 (23%)
CG8195	NP_611049.1	EamA	260..403	CDD:279264	29/116 (25%)
SLC35A5	NP_001335834.1	Nuc_sug_transp	24..374	CDD:282054	36/155 (23%)
SLC35A5	NP_001335834.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	397..424
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0697
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900